Integrin Alpha2b antibody

Catalog No. ABIN210179

Product Details anti-Integrin Alpha2b Antibody

Target: Integrin Alpha2b (CD41)

Reactivity: Human, Baboon, Mink

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin Alpha2b antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB)

Specificity: Recognizes the human CD41 cell surface antigen, a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF. It has not been established if clone Recognizes free CD41 or CD41 only when complexed with CD61. However, antibody binding is reduced in the presence of EDTA suggesting that the epitope recognized is dependent upon an intact CD41/61 complex.

Purification: Protein G purified

Immunogen: Human platelet plasma membrane.

Type of Immunogen: Membrane preparation

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:100 - 1:200), WB

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 100 μL human whole blood. Method sheets are available on request. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Reconstitution: deionized water

Concentration: Lot specific

Preservative: Azide free

Storage: -20 °C

Storage Comment: Short term: -20°C
Long term: -20°C.

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: ITGA2B / CD41 (CD41 Products)

Background: Name/Gene ID: ITGA2B
Family: Integrin

Synonyms: ITGA2B, BDPLT2, CD41B, GT, gp2B, Integrin alpha-IIb, ITGAB, GPIIb, HPA3, Platelet-specific antigen BAK, CD41, CD41 antigen, GPalpha IIb, GTA

Gene ID: 3674

Pathways: Integrin Complex