Integrin Alpha2b antibody (CD41) (FITC)

Details for Product anti-CD41 Antibody No. ABIN94108
Antigen
Reactivity
Human
369
95
28
16
11
9
5
4
2
2
2
2
1
1
1
1
Host
Mouse
298
76
60
Clonality (Clone)
Monoclonal ()
Conjugate
This Integrin Alpha2b antibody is conjugated to FITC
58
42
41
15
10
6
5
5
4
3
3
3
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
306
93
75
71
56
49
33
20
20
13
7
6
6
3
3
1
1
1
Options
Immunogen Leukocytes of patient suffering from LGL-type leukaemia.
Clone MEM-06
Isotype IgG1
Specificity The antibody MEM-06 reacts with CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain, 120 kDa) and GPIIb beta (light chain, 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.
Workshop: HLDA 10
Cross-Reactivity (Details) Human
Antigen
Alternative Name CD41 (CD41 Antibody Abstract)
Background CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.
Pathways Integrin Complex
Application Notes The reagent is designed for Flow Cytometry analysis of human blood cells using 20 μ,l reagent / 100 μ,l of whole blood or 106 cells in a suspension.The content of a vial (2 ml) is sufficient for 100 tests.
Comment

The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.

Restrictions For Research Use only
Reconstitution No reconstitution is necessary.
Buffer The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Avoid prolonged exposure to light.
Storage 4 °C
Storage Comment Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
Supplier Images
Image no. 1 for anti-Integrin Alpha2b (CD41) antibody (FITC) (ABIN94108) Surface staining of human platelets with anti-human CD41 (MEM-06) PE.