Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Integrin Alpha2b antibody (AA 351-450)

CD41 Reactivity: Human, Rat FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN748358
  • Target See all Integrin Alpha2b (CD41) Antibodies
    Integrin Alpha2b (CD41)
    Binding Specificity
    • 15
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    Reactivity
    • 115
    • 29
    • 20
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 75
    • 42
    • 20
    Rabbit
    Clonality
    • 92
    • 39
    • 1
    Polyclonal
    Conjugate
    • 56
    • 15
    • 13
    • 12
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Integrin Alpha2b antibody is un-conjugated
    Application
    • 99
    • 43
    • 31
    • 26
    • 19
    • 18
    • 12
    • 12
    • 9
    • 9
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Rat
    Predicted Reactivity
    Mouse,Cow,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from mouse Integrin alpha 2b
    Isotype
    IgG
    Top Product
    Discover our top product CD41 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Sugiyama, Gamage, Zyla, Armstrong, Advani, Advani, Wang, Lee: "Influenza Virus Infection Induces Platelet-Endothelial Adhesion Which Contributes to Lung Injury." in: Journal of virology, Vol. 90, Issue 4, pp. 1812-23, (2016) (PubMed).

    Araki, Ogawara, Suzuki, Kawai, Watanabe, Ono, Higaki: "Augmented EPR effect by photo-triggered tumor vascular treatment improved therapeutic efficacy of liposomal paclitaxel in mice bearing tumors with low permeable vasculature." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 200, pp. 106-14, (2015) (PubMed).

    Lê, Schneider, Boergeling, Berri, Ducatez, Guerin, Adrian, Errazuriz-Cerda, Frasquilho, Antunes, Lina, Bordet, Jandrot-Perrus, Ludwig, Riteau: "Platelet Activation and Aggregation Promote Lung Inflammation and Influenza Virus Pathogenesis." in: American journal of respiratory and critical care medicine, (2015) (PubMed).

    Mei, Yin, Jin, He, Yin: "The regulatory role of the adrenergic agonists phenylephrine and isoproterenol on fetal hemoglobin expression and erythroid differentiation." in: Endocrinology, Vol. 154, Issue 12, pp. 4640-9, (2013) (PubMed).

  • Target
    Integrin Alpha2b (CD41)
    Alternative Name
    Integrin alpha 2b/CD41 (CD41 Products)
    Synonyms
    AI172977 antibody, CD41 antibody, CD41B antibody, GpIIb antibody, alphaIIb antibody, BDPLT16 antibody, BDPLT2 antibody, GP2B antibody, GPIIb antibody, GT antibody, GTA antibody, HPA3 antibody, integrin alpha 2b antibody, integrin subunit alpha 2b antibody, Itga2b antibody, ITGA2B antibody
    Background

    Synonyms: CD41, CD41B, GpIIb, AI172977, alphaIIb, Integrin alpha-IIb, GPalpha IIb, Platelet membrane glycoprotein IIb, Itga2b

    Background: Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

    Gene ID
    16399
    UniProt
    Q9QUM0
    Pathways
    Integrin Complex
You are here:
Support