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CD40 antibody (Extracellular Domain)

CD40 Reactivity: Mouse FACS, ELISA, IHC, Func, IHC (fro) Host: Rat Monoclonal unconjugated

Catalog No. ABIN217603

Datasheet as PDF

Target See all CD40 Antibodies

CD40
Binding Specificity
18

17

16

14

14

10

9

5

4

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Extracellular Domain
Reactivity
182

103

19

19

8

6

6

5

4

3

2

2

2

2

1
Mouse
Host
107

95

47

5

3

1
Rat
Compatible Secondaries
Clonality
166

83

7
Monoclonal
Conjugate
129

23

23

15

11

5

4

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD40 antibody is un-conjugated
Application
161

87

61

50

36

28

23

20

17

14

13

12

5

4

4

4

4

4

4

3

3

3

2

2

2

1
Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity

Recognizes the murine CD40 cell surface glycoprotein. It does not react with normal mouse Ig or with human IgG1 and will stain most mature mouse B cells. It does not cross react with mouse T cells. The specificity ofwas demonstrated by ELISA and flow cytometry using BHK cells transfected with mouse CD40. Is a powerful activator of normal B cells especially in the presence of IL-4.

Purification

Protein G purified

Endotoxin Level

Low Endotoxin

Immunogen

Extracellular Domain of Mouse CD40 and the Fc portion of Human IgG1.

Type of Immunogen: Fusion protein

Isotype

IgG2a

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CD40 Reactivity: Human FACS, IHC, IF, StM, DNA Mic Host: Mouse Monoclonal C40-1605 unconjugated

anti-CD40 (CD40) (C-Term) antibody
CD40 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-CD40 (CD40) (AA 21-193) antibody
CD40 Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 4C3B8 unconjugated

anti-CD40 (CD40) (AA 29-107) antibody
CD40 Reactivity: Human FACS, ELISA, IHC, StM, Coat Host: Mouse Monoclonal C40-2383 unconjugated

anti-CD40 (CD40) (AA 1-360) antibody
CD40 Reactivity: Human, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-CD40 (CD40) (Extracellular Domain) antibody
CD40 Reactivity: Human FACS, IHC, St Host: Mouse Monoclonal 5C3 unconjugated

anti-CD40 (CD40) antibody
CD40 Reactivity: Human FACS Host: Mouse Monoclonal HI40a unconjugated

anti-CD40 (CD40) antibody (FITC)
CD40 Reactivity: Human FACS Host: Mouse Monoclonal HI40a FITC

anti-CD40 (CD40) antibody
CD40 Reactivity: Human FACS, IHC, IP, Act Host: Rabbit Chimeric G28-5 unconjugated Recombinant Antibody

Application Notes

Approved: ELISA, Flo (1:50), Func, IHC, IHC-Fr

Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request.

Comment

Target Species of Antibody: Mouse

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

PBS,  pH 7.4.
Target

CD40

Alternative Name

CD40 (CD40 Products)

Background

Name/Gene ID: CD40
Family: TNF Receptor

Synonyms: CD40, B-cell surface antigen CD40, B cell-associated molecule, B cell surface antigen CD40, CD40 antigen, CD40 type II isoform, p50, Bp50, CD40L receptor, CDW40, TNFRSF5

Gene ID

958

Pathways

NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints