CD28 antibody
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- Target See all CD28 Antibodies
- CD28
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Reactivity
- Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD28 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Functional Studies (Func)
- Specificity
- The JJ319 monoclonal antibody specifically reacts with rat CD28, a 44 kDa glycoprotein member of the immunoglobulin superfamily.
- Purification
- The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
- Clone
- JJ319
- Isotype
- IgG1
- Top Product
- Discover our top product CD28 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Phosphate-buffered aqueous solution, ph7.2.
- Storage
- 4 °C
- Storage Comment
- The product should be stored undiluted at 4°C. Do not freeze.
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- Target
- CD28
- Alternative Name
- CD28 (CD28 Products)
- Background
- The JJ319 monoclonal antibody specifically reacts with rat CD28, a 44 kDa glycoprotein member of the immunoglobulin superfamily. CD28 is expressed on alpha/beta TCR+ T cells, some gamma/delta TCR+ T cells and a subset of NK cells. CD28 is a costimulatory receptor required for T cell activation. Its ligands are CD80 (B7-1) and CD86 (B7-2).
- Gene ID
- 25660
- UniProt
- P31042
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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