TNFRSF10A antibody (Biotin)

Catalog No. ABIN2629377

Product Details anti-TNFRSF10A Antibody (Biotin)

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFRSF10A antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), Functional Studies (Func)

Specificity: Recognizes human TRAIL-R1. Does not cross-react with human TRAIL-R2, -R3 or -R4.

Purification: Protein G purified from tissue culture supernatant

Immunogen: Recombinant human TRAIL-R1 (DR4).

Type of Immunogen: Recombinant protein

Clone: HS101

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, Func, ICC, IP

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Functional Application - Inhibition (blocks TRAIL-R1 mediated killing if applied in solution.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for TNFRSF10A

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Alternative Name: TNFRSF10A / DR4 (TNFRSF10A Products)

Background: Name/Gene ID: TNFRSF10A
Family: TNF Receptor

Synonyms: TNFRSF10A, APO2, CD261, DR4, TRAIL-R1, TRAILR-1, TRAILR1, TRAIL receptor 1, CD261 antigen, Cytotoxic TRAIL receptor, Death receptor 4

Gene ID: 8797

Pathways: Apoptosis, Positive Regulation of Endopeptidase Activity