CD3 antibody (Alexa Fluor 647)

Catalog No. ABIN2656799

Product Details anti-CD3 Antibody (Alexa Fluor 647)

Target: CD3

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD3 antibody is conjugated to Alexa Fluor 647

Application: Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)

Purification: The antibody was conjugated with Alexa Fluor® 488 under optimal conditions.

Purity: The antibody is at > 85 % purity.

Clone: 1F4

Isotype: IgM kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C

Target Details for CD3

Target: CD3

Alternative Name: CD3 (CD3 Products)

Background: CD3 is a complex composed of δ, γ, ε, and ζ chains. They are 20-25 kD members of the immunoglobulin superfamily and associated with the T cell receptor (TCR). CD3 is expressed on thymocytes, peripheral T cells, some NK-T cells, and dendritic epidermal T cells. CD3 is involved in antigen recognition, signal transduction, and T cell activation.

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway