Bcl-2 antibody (AA 41-54) (Alexa Fluor 647)
-
- Target See all Bcl-2 (BCL2) Antibodies
- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
-
Binding Specificity
- AA 41-54
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This Bcl-2 antibody is conjugated to Alexa Fluor 647
-
Application
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- Purification
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
- Immunogen
- AA 41-54 of human bcl-2 oncoprotein
- Clone
- 1E2
- Isotype
- IgG1
- Top Product
- Discover our top product BCL2 Primary Antibody
-
anti-B-Cell CLL/lymphoma 2 (BCL2) (N-Term) antibody
BCL2 Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 2-211) antibodyBCL2 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 101-160) antibodyBCL2 Reactivity: Human, Mouse, Rat, Rabbit, Cow, Chicken, Bacteria WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 1-100) antibodyBCL2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 75-110) antibodyBCL2 Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal RB04684 unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) antibodyBCL2 Reactivity: Human WB, IHC, IP Host: Rabbit Monoclonal unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 2-211) antibodyBCL2 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal D1 unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibodyBCL2 Reactivity: Human WB, FACS, IP, IHC (p), ICC, IHC (fro) Host: Mouse Monoclonal Bcl-2-100 unconjugated
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 41-54) antibody (PE)BCL2 Reactivity: Human FACS Host: Mouse Monoclonal Bcl-2-100 PE
anti-B-Cell CLL/lymphoma 2 (BCL2) antibodyBCL2 Reactivity: Human WB, IHC, StM Host: Rabbit Monoclonal BCL2-2210R unconjugated Recombinant Antibody
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Protect from prolonged exposure to light. Do not freeze.
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C
-
- Target
- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
- Alternative Name
- Bcl-2 (BCL2 Products)
- Background
- Bcl-2 is a conserved anti-apoptotic protein that plays important roles in normal immunity. It forms homodimers or heterodimers with other Bcl-2 family members. This protein regulates apoptosis through controlling mitochondrial fusion and fission. Phosphorylation of Bcl-2 has been shown to enhance activity to allow response to extracellular growth-factor-mediated signals. Bcl-2 is also regulated by IRES, miR-15a, miR-16-1 and RNA-BP nucleolin. Chromosome 18q21.3 translocation and overexpression of Bcl-2 is frequently observed in follicular lymphomas and some diffuse large B-cell lymphomas.
- Pathways
- MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
-
