Bcl-2 antibody (AA 101-160)

Catalog No. ABIN723920

There are 4+ publications for this product available. The Rabbit Polyclonal anti-Bcl-2 antibody is suitable to detect Bcl-2 in samples from Human. It has been validated for WB, IF, IHC (p) and IHC (fro).

Quick Overview for Bcl-2 antibody (AA 101-160) (ABIN723920)

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Bcl-2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Bcl-2 Antibody

Binding Specificity: AA 101-160

Purpose: Bcl-2 Polyclonal Antibody

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Bcl-2

Isotype: IgG

Application Details

Application Notes: WB(1:500-2000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Bcl-2 antibody (ABIN723920)

She, Zhao, Zhu, Han, Xia, Bai, Zhang, Li: "Aluminum Trichloride Disorders Bile Acid Secretion and Induces Hepatocyte Apoptosis in Rats." in: Cell biochemistry and biophysics, (2015) (PubMed).

He, Song, Liu, Chen, Hua: "Rapamycin inhibits acrolein-induced apoptosis by alleviating ROS-driven mitochondrial dysfunction in male germ cells." in: Cell proliferation, Vol. 47, Issue 2, pp. 161-71, (2014) (PubMed).

Tian, Zhang, Wang, Dai, Shen, Yang, Huang: "The protective effect of hyperbaric oxygen and Ginkgo biloba extract on A?25-35-induced oxidative stress and neuronal apoptosis in rats." in: Behavioural brain research, Vol. 242, pp. 1-8, (2013) (PubMed).

Chen, Shi, Liu, Fang, Zhang, Zhao: "Targeting SPARC by lentivirus-mediated RNA interference inhibits cervical cancer cell growth and metastasis." in: BMC cancer, Vol. 12, pp. 464, (2012) (PubMed).

Target Details for Bcl-2

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Alternative Name: Bcl-2

Background: Synonyms: Apoptosis regulator Bcl 2, Apoptosis regulator Bcl2, AW986256, B cell CLL/lymphoma 2, B cell leukemia/lymphoma 2, B cell lymphoma 2, Bcl 2, Bcl-2, Bcl2, BCL2 protein, C430015F12Rik, D630044D05Rik, D830018M01Rik, Leukemia/lymphoma, B-cell, 2, Oncogene B-cell leukemia 2, BCL2_HUMAN.

Gene ID: 596

UniProt: P10415

Pathways: MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling