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CD80 antibody (Alexa Fluor 647)

Name: CD80 antibody (Alexa Fluor 647)
SKU: ABIN2657846
Availability: OutOfStock

CD80 Reactivity: Mouse FACS, IHC, CyTOF Host: Hamster Monoclonal 16-10A1 Alexa Fluor 647

FACS

1 image

Catalog No. ABIN2657846

Datasheet as PDF

Target See all CD80 Antibodies

CD80
Reactivity
140

100

45

6

6

5

1

1

1
Mouse
Host
91

72

20

20

10

2

1
Hamster
Clonality
134

79

2
Monoclonal
Conjugate
90

19

17

16

11

5

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This CD80 antibody is conjugated to Alexa Fluor 647
Application
126

90

66

35

33

22

14

13

13

12

11

10

8

5

4

2

2

2

1

1

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Cytometry by Time of Flight (CyTOF)

Cross-Reactivity

Dog (Canine)

Purification

The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

Clone

16-10A1

Isotype

IgG

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anti-CD80 (CD80) antibody
CD80 Reactivity: Mouse, Dog FACS, IP, IHC (fro) Host: Armenian Hamster Monoclonal 16-10A1 unconjugated

anti-CD80 (CD80) (AA 38-246) antibody
CD80 Reactivity: Mouse WB, IP, IHC, ICC Host: Rabbit Polyclonal unconjugated

anti-CD80 (CD80) (Extracellular Domain) antibody
CD80 Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-233 unconjugated

anti-CD80 (CD80) (AA 251-321) antibody
CD80 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated

anti-CD80 (CD80) (Extracellular Domain) antibody (FITC)
CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 FITC

anti-CD80 (CD80) (Extracellular Domain) antibody (PerCP)
CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 PerCP

anti-CD80 (CD80) (Extracellular Domain) antibody (APC)
CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 APC

anti-CD80 (CD80) (Extracellular Domain) antibody (PE)
CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 PE

anti-CD80 (CD80) antibody
CD80 Reactivity: Human ELISA, IHC, ICC Host: Mouse Monoclonal 2A2 unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Concentration

0.5 mg/mL

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Protect from prolonged exposure to light. Do not freeze.

Storage

4 °C

Storage Comment

The antibody solution should be stored undiluted between 2°C and 8°C
Target

CD80

Alternative Name

CD80 (CD80 Products)

Background

CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Pathways

TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints