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TCR V Alpha7.2 antibody (APC-Cy7)

This Mouse Monoclonal antibody specifically detects in FACS, IP and WB. It exhibits reactivity toward Human.
Catalog No. ABIN2660625

Quick Overview for TCR V Alpha7.2 antibody (APC-Cy7) (ABIN2660625)

Target

TCR V Alpha7.2

Reactivity

Human

Host

Mouse

Clonality

Monoclonal

Conjugate

APC-Cy7

Application

Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)

Clone

3C10
  • Characteristics

    The 3C10 antibody recognizes the Vα7.2 T cell antigen receptor (TCR) α -chain segment which, joined with the Jα33 segment, constitutes an invariant TCR that is characteristics of the mucosal-associated invariant T cells (MAIT cells). MAIT cells are restricted by a nonpolymorphic class Ib major histocompatibility complex (MHC) molecule, MHC-related molecule 1 (MR1). MAIT cells are present in human blood (1-8 % of T cells), mesenteric lymph nodes, liver, and intestinal mucosa. MAIT cells play a role in detecting and fighting off microbial infections.

    Purification

    The antibody was purified by affinity chromatography and conjugated with APC/Cy7 under optimal conditions. The solution is free of unconjugated APC/Cy7 and unconjugated antibody.

    Isotype

    IgG1 kappa
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Buffer

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Protect from prolonged exposure to light. Do not freeze.

    Storage

    4 °C

    Storage Comment

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target

    TCR V Alpha7.2
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