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IL2RG antibody
IL2RG
Reactivity: Human
FACS
Host: Rat
Monoclonal
TUGh4
unconjugated
Product Details anti-IL2RG Antibody
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Target
See all IL2RG Antibodies
IL2RG
(Interleukin 2 Receptor, gamma (IL2RG))
Reactivity
All reactivities for IL2RG antibodies
Human
Host
All hosts for IL2RG antibodies
Rat
Clonality
All clonalities for IL2RG antibodies
Monoclonal
Conjugate
All conjugates for IL2RG antibodies
This IL2RG antibody is un-conjugated
Application
All applications for IL2RG antibodies
Flow Cytometry (FACS)
Cross-Reactivity
Dog (Canine)
Purification
The antibody was purified by affinity chromatography.
Clone
TUGh4
Isotype
IgG2b kappa
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for IL2RG
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Target
IL2RG
(Interleukin 2 Receptor, gamma (IL2RG))
Alternative Name
CD132 (IL2RG Products )
Background
CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, also known as common γ chain (γc), or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).
Pathways
JAK-STAT Signaling , Growth Factor Binding
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