IL2RG antibody (AA 23-262)

Catalog No. ABIN7193309

Product Details anti-IL2RG Antibody

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Binding Specificity: AA 23-262

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL2RG antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)

Purification: purified

Immunogen: Purified recombinant fragment of human CD132 (AA: extra 23-262) expressed in E. coli.

Clone: 4A8F2

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: N/A, ICC: N/A, IHC: N/A

Restrictions: For Research Use only

Handling

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for IL2RG

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Alternative Name: CD132 (IL2RG Products)

Synonyms: Ab2-183 antibody, Cd132 antibody, CD132 antibody, CIDX antibody, IL-2RG antibody, IMD4 antibody, P64 antibody, SCIDX antibody, SCIDX1 antibody, [g]c antibody, gamma(c) antibody, gc antibody, interleukin 2 receptor subunit gamma antibody, interleukin 2 receptor subunit gamma L homeolog antibody, interleukin 2 receptor, gamma chain antibody, IL2RG antibody, il2rg.L antibody, Il2rg antibody

Background:

Description: The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.

Aliases: IL2RG, P64, CIDX, IMD4, SCIDX, IL-2RG, SCIDX1

Molecular Weight: 42.3 kDa

Gene ID: 3561

Pathways: JAK-STAT Signaling, Growth Factor Binding