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BAFF antibody

TNFSF13B Reactivity: Human FACS Host: Mouse Monoclonal 1D6 unconjugated
Catalog No. ABIN2664449
  • Target See all BAFF (TNFSF13B) Antibodies
    BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
    Reactivity
    • 118
    • 29
    • 28
    • 2
    • 2
    • 2
    Human
    Host
    • 77
    • 40
    • 13
    • 10
    Mouse
    Clonality
    • 88
    • 52
    Monoclonal
    Conjugate
    • 73
    • 17
    • 10
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BAFF antibody is un-conjugated
    Application
    • 76
    • 57
    • 47
    • 30
    • 15
    • 15
    • 13
    • 13
    • 11
    • 10
    • 8
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography.
    Clone
    1D6
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product TNFSF13B Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
    Alternative Name
    CD257 (TNFSF13B Products)
    Background
    BAFF, also known as B cell activating factor, tumor necrosis factor ligand superfamily 13B, B lymphocyte stimulator (BLYS), TNF and APOL-related leukocyte expressed ligand 1 (TALL1), and TNF homolog, activates apoptosis, NF-κ B, and JNK (THANK). BAFF is a type II transmembrane protein and is a member of the tumor necrosis factor ligand superfamily. BAFF can be proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homotrimers. The predicted molecular weight of a BAFF monomer is approximately 31 kD. BAFF is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells. It is upregulated by IFN-γ and downregulated by PMA/ionomycin treatment.
    Pathways
    NF-kappaB Signaling, Production of Molecular Mediator of Immune Response
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