Prostaglandin D2 Receptor 2 (PTGDR2) antibody

Catalog No. ABIN2664521

This anti- antibody is a Rat Monoclonal antibody detecting in FACS. Suitable for Human.

Quick Overview for Prostaglandin D2 Receptor 2 (PTGDR2) antibody (ABIN2664521)

Target: Prostaglandin D2 Receptor 2 (PTGDR2)

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Flow Cytometry (FACS)

Clone: BM16

Product Details

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details

Target: Prostaglandin D2 Receptor 2 (PTGDR2)

Alternative Name: CD294

Background: CD294, also known as CRTH2, is a seven-transmembrane protein coupled with heterotrimeric G proteins. CRTH2 is the prostaglandin D2 receptor and is expressed by Th2 cells, eosinophils, and basophils. CD294 prevents the apoptosis of Th2 cells and mediates the chemotaxis of CRTH2 expressing cells to the sites of allergic inflammation, such as the asthmatic lung.

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling