Selectin E/CD62e antibody
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- Target See all Selectin E/CD62e (SELE) Antibodies
- Selectin E/CD62e (SELE) (Selectin E (SELE))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Selectin E/CD62e antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS)
- Purification
- The antibody was purified by affinity chromatography.
- Clone
- HCD62E
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product SELE Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- Selectin E/CD62e (SELE) (Selectin E (SELE))
- Alternative Name
- CD62E (SELE Products)
- Background
- CD62E (also known as E-selectin, ELAM-1, and LECAM-1) is a 115 kD type I membrane protein and a member of the selectin family. CD62E is highly expressed on activated endothelial cells (IL-2, TNF-α, other cytokines can increase expression) and can also be expressed on endothelial cells in the skin, bone marrow and placenta. CD62E is involved in tethering and leucocyte rolling on activated endothelium at inflammatory sites and may also play a role in tumor metastasis and angiogenesis. CD62E binds to both Siayl Lewis X (CD15s) and PSGL-1 (CD162). The HCD62E antibody has been shown to recognize human CD62E and to be useful for flow cytometry.
- Pathways
- Thromboxane A2 Receptor Signaling
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