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- Target See all KLRK1 Antibodies
- KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This KLRK1 antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Brand
- Ultra-LEAF™
- Purification
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
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Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.
- Clone
- 1D11
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product KLRK1 Primary Antibody
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anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 73-216) antibody
KLRK1 Reactivity: Human WB, FACS, ELISA Host: Mouse Monoclonal 5C9B4 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 121-219) antibodyKLRK1 Reactivity: Mouse WB, FACS, ELISA, IHC (fro), IF (cc), IF (p), IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) antibody (FITC)KLRK1 Reactivity: Human FACS Host: Mouse Monoclonal 1D11 FITC
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) antibodyKLRK1 Reactivity: Human FACS, IP, IHC (fro), Func Host: Mouse Monoclonal 1D11 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) antibodyKLRK1 Reactivity: Human FACS, IP, IHC (fro) Host: Mouse Monoclonal 1D11 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 167-216) antibodyKLRK1 Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 73-216) antibodyKLRK1 Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 92-216) antibodyKLRK1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 90-232) antibodyKLRK1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1) (AA 75-215) antibodyKLRK1 Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Preservative
- Azide free
- Handling Advice
- This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))
- Alternative Name
- CD314 (KLRK1 Products)
- Background
- CD314 is a homodimeric C-type lectin-like protein also known as NKG2D. It is expressed on NK cells, CD8+ T cells, γ/ δ T cells, and in vitro induced LAK cells. Several molecules have been identified as the ligands for NKG2D, including MHC class-I chain-related protein A (MICA), MICB, and UL16-binding proteins (ULBPs). NKG2D has no intrinsic signaling capacity, but attains this by non-covalent association with DAP10 or DAP12 adaptors. In addition to being a primary activation receptor on NK cells, NKG2D is also a costimulatory receptor for TCR-mediated T cell proliferation and cytokine production. The interaction of NKG2D with its ligands plays a role in the immune surveillance against pathogen and tumor cells, and in the pathogenesis of autoimmune diseases.
- Pathways
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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