ADRP antibody (N-Term)

Catalog No. ABIN285650

The Guinea Pig Polyclonal anti-ADRP antibody has been validated for WB, IHC (p) and IHC (fro). It is suitable to detect ADRP in samples from Human. There are 17+ publications available.

Quick Overview for ADRP antibody (N-Term) (ABIN285650)

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Reactivity: Human

Host: Guinea Pig

Clonality: Polyclonal

Conjugate: This ADRP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ADRP Antibody

Binding Specificity: AA 1-29, N-Term

Purity: Whole antiserum

Immunogen: Adipophilin antibody was raised in guinea pig using a synthetic peptide corresponding to residues 1-29 of the N-terminus of human and murine adipophilin as the immunogen.

Application Details

Application Notes: IHC-F: 1:100, IHC-P: 1:100, WB: 1:2,000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as whole antiserum with 0.09 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

Storage: 4 °C

Storage Comment: Store at 4 °C

References for anti-ADRP antibody (ABIN285650)

Yuan, Klinkhammer, Lyu, Gao, Yuan, Hopkins, Zhang, De Langhe: "Temporospatial Expression of Fgfr1 and 2 During Lung Development, Homeostasis, and Regeneration." in: Frontiers in pharmacology, Vol. 11, pp. 120, (2020) (PubMed).

Ali, Assiri, Harris, Michel, Yun, Marentette, Huynh, Orlicky, Shearn, Saba, Reisdorph, Reisdorph, Hirschey, Fritz: "Quantifying Competition among Mitochondrial Protein Acylation Events Induced by Ethanol Metabolism." in: Journal of proteome research, Vol. 18, Issue 4, pp. 1513-1531, (2020) (PubMed).

Mardani, Tomas Dalen, Drevinge, Miljanovic, Ståhlman, Klevstig, Scharin Täng, Fogelstrand, Levin, Ekstrand, Nair, Redfors, Omerovic, Andersson, Kimmel, Borén, Levin: "Plin2-deficiency reduces lipophagy and results in increased lipid accumulation in the heart." in: Scientific reports, Vol. 9, Issue 1, pp. 6909, (2019) (PubMed).

Sánchez-Danés, Larsimont, Liagre, Muñoz-Couselo, Lapouge, Brisebarre, Dubois, Suppa, Sukumaran, Del Marmol, Tabernero, Blanpain: "A slow-cycling LGR5 tumour population mediates basal cell carcinoma relapse after therapy." in: Nature, Vol. 562, Issue 7727, pp. 434-438, (2019) (PubMed).

Zwick, Rudolph, Shook, Holtrup, Roth, Lei, Van Keymeulen, Seewaldt, Kwei, Wysolmerski, Rodeheffer, Horsley: "Adipocyte hypertrophy and lipid dynamics underlie mammary gland remodeling after lactation." in: Nature communications, Vol. 9, Issue 1, pp. 3592, (2018) (PubMed).

Mulye, Zapata, Gilk: "Altering lipid droplet homeostasis affects Coxiella burnetii intracellular growth." in: PLoS ONE, Vol. 13, Issue 2, pp. e0192215, (2018) (PubMed).

Toledo, Roque, Teixeira, Milán-Garcés, Carneiro, Almeida, Andrade, Martins, Pinho, Freire-de-Lima, Bozza, DAvila, Melo: "Lipid Body Organelles within the Parasite Trypanosoma cruzi: A Role for Intracellular Arachidonic Acid Metabolism." in: PLoS ONE, Vol. 11, Issue 8, pp. e0160433, (2017) (PubMed).

Chang, Khatchadourian, McKinney, Maysinger: "Docosahexaenoic acid (DHA): a modulator of microglia activity and dendritic spine morphology." in: Journal of neuroinflammation, Vol. 12, pp. 34, (2016) (PubMed).

Smagris, Gilyard, BasuRay, Cohen, Hobbs: "Inactivation of Tm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins." in: The Journal of biological chemistry, Vol. 291, Issue 20, pp. 10659-76, (2016) (PubMed).

Zhou, Park, Xu, Xia, Ye, Su, Jeong, Hur, Oh, Tamori, Zingaretti, Cinti, Argente, Yu, Wu, Ju, Guan, Yang, Choi, Savage, Li: "Insulin resistance and white adipose tissue inflammation are uncoupled in energetically challenged Fsp27-deficient mice." in: Nature communications, Vol. 6, pp. 5949, (2015) (PubMed).

Jiang, Hurt, Breen, Stabler, Allen, Orlicky, Maclean: "Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap." in: Biology open, Vol. 4, Issue 9, pp. 1154-62, (2015) (PubMed).

Kijani, Yrlid, Heyden, Levin, Borén, Fogelstrand: "Filter-Dense Multicolor Microscopy." in: PLoS ONE, Vol. 10, Issue 3, pp. e0119499, (2015) (PubMed).

Kozlitina, Smagris, Stender, Nordestgaard, Zhou, Tybjærg-Hansen, Vogt, Hobbs, Cohen: "Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease." in: Nature genetics, Vol. 46, Issue 4, pp. 352-6, (2014) (PubMed).

Sitnick, Basantani, Cai, Schoiswohl, Yazbeck, Distefano, Ritov, DeLany, Schreiber, Stolz, Gardner, Kienesberger, Pulinilkunnil, Zechner, Goodpaster, Coen, Kershaw: "Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity." in: Diabetes, Vol. 62, Issue 10, pp. 3350-61, (2013) (PubMed).

Frances, Niemann: "Stem cell dynamics in sebaceous gland morphogenesis in mouse skin." in: Developmental biology, Vol. 363, Issue 1, pp. 138-46, (2012) (PubMed).

Bandeira-Melo, Weller, Bozza: "Identifying intracellular sites of eicosanoid lipid mediator synthesis with EicosaCell assays." in: Methods in molecular biology (Clifton, N.J.), Vol. 717, pp. 277-89, (2011) (PubMed).

Hartman, Liu, Zehmer, Luby-Phelps, Jo, Anderson, DeBose-Boyd: "Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from endoplasmic reticulum membranes into the cytosol through a subcellular compartment resembling lipid droplets." in: The Journal of biological chemistry, Vol. 285, Issue 25, pp. 19288-98, (2010) (PubMed).

Target Details for ADRP

Target: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Alternative Name: Adipophilin

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism