CD79a antibody (AA 202-216) (PE)

Catalog No. ABIN316541

This Mouse Monoclonal antibody specifically detects CD79a in FACS. It exhibits reactivity toward Human, Mouse, Rat, Cow, Pig, Monkey, Chicken, Rabbit, Horse, Guinea Pig and Dog.

Quick Overview for CD79a antibody (AA 202-216) (PE) (ABIN316541)

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Reactivity: Human, Mouse, Rat, Cow, Pig, Monkey, Chicken, Rabbit, Horse, Guinea Pig, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD79a antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: HM57

Product Details anti-CD79a Antibody (PE)

Binding Specificity: AA 202-216

Specificity: This antibody recognises an epitope within the cytoplasmic domain of CD79a. CD79a, also known as mb-1, is a 45 kDa protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells.

Characteristics: Synonyms: IGA, MB1, B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain,MB-1 membrane glycoprotein, Surface IgM-associated protein, Membrane-boundimmunoglobulin-associated protein

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogen: Synthetic peptide corresponding to 202-216 amino acid sequence of human mb-1

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry: use 10 μL of neat antibody to label 1x10^6 cells in 100 μL, Membranepermeabilisation is required for this application.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Reconstitute with 0.25 mL distilled water

Concentration: 0.1 mg/mL

Buffer: Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3), 1 % Bovine Serum Albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 2-8 °C. DO NOT FREEZE. This product is photosensitive and should be protected from light. Should this productcontain a precipitate we recommend microcentrifugation before use.
Shelf life: One year from despatch.

Expiry Date: 12 months

Target Details for CD79a

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Alternative Name: CD79a

Background: The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signalling following antigen-binding to surface immunoglobulin.Synonyms: B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain, IGA, MB-1 membrane glycoprotein, MB1, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein

Gene ID: 973

UniProt: P11912

Pathways: BCR Signaling