CD94 antibody

Catalog No. ABIN316802

Product Details anti-CD94 Antibody

Target: CD94 (KLRD1) (Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD94 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Specificity: This antibody is specific for CD94, also known as KLRD1 (Killer cell lectin-like receptor, subfamily D, member 1). Clone DX22 is reported to inhibit the binding of CD94 to HLA-E(2) and HLA-G(4). We recommend the use of AM05552AF-N for functional studies.

Characteristics: Synonyms: NK cell receptor, KP43, NK cell marker, KLRD-1, Natural killer cells antigen CD94, Killer celllectin-like receptor subfamily D member 1

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogen: Natural killer cell line. Spleen cells from immunised BALB/c mice were fused with cells of the SP2/0 myeloma cellline.

Clone: DX22

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry: Use 10 μL of 1/50-1/100 diluted antibody to label 1 x 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CD94

Target: CD94 (KLRD1) (Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))

Alternative Name: CD94 (KLRD1 Products)

Background: CD94 is expressed on natural killer (NK) cells and a subset of T lymphocytes. CD94 is found to associate with NKG2 to form a heterodimer which is involved in the inhibition of cell mediated cytotoxicity against cells bearing appropriate MHC class I allotypes.Synonyms: KLRD1, KP43, Killer cell lectin-like receptor subfamily D member 1, NK cell receptor, Natural killer cells antigen CD94

Gene ID: 3824

UniProt: Q13241