Fibroblast Growth Factor Receptor 2 (FGFR2) (Internal Region) antibody

Details for Product No. ABIN334399
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Antigen
Synonyms
FGFR2, FGFR2IIIb, bek, bfr-1, cd332, cek3, cfd1, ect1, fgfr-2, jws, k-sam, kgfr, tk14, tk25, xfgfr2, DKFZp469H1521, BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25, AU043015, A ... show more
FGFR2, FGFR2IIIb, bek, bfr-1, cd332, cek3, cfd1, ect1, fgfr-2, jws, k-sam, kgfr, tk14, tk25, xfgfr2, DKFZp469H1521, BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25, AU043015, AW556123, Bek, Fgfr-2, Fgfr-7, Fgfr7, KGFRTr, svs, FGF-R, fgfr72IIIb, FGFR, fc56c05, wu:fc56c05 show less
Epitope
Internal Region
(23), (18), (12), (12), (6), (6), (5), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(141), (43), (36), (3), (2)
Host
Goat
(120), (24), (2), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (5), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Methode Type Peptide ELISA
Application
ELISA, Western Blotting (WB)
(115), (61), (46), (40), (39), (26), (15), (10), (7), (2)
Pubmed 2 references available
Quantity 100 µg
Options
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Catalog No. ABIN334399
374.27 $
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Immunogen Peptide with sequence C-GREKEITASPDY, from the internal region of the protein sequence according to NP_000132.3, NP_075259.4, NP_001138385.1, NP_001138386.1, NP_001138387.1, NP_001138388.1, NP_001138390.1, NP_001138391.1.
Specificity This antibody is expected to recognise all reported isoforms except isoform 7 (NP_001138389.1). The immunizing peptide represents part of the extracellular domain.
Cross-Reactivity Mouse (Murine), Rat (Rattus), Dog (Canine), Pig (Porcine), Cow (Bovine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name FGFR2
Background Synonyms: FGFR2, fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome), BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM
Gene ID 2263, 14183, 25022
NCBI Accession NP_000132, NP_001138387, NP_001138388, NP_001138386, NP_001138385, NP_001138391, NP_001138390, NP_075259
Research Area Growth Factors, Lineage Markers, Tyrosine Kinases, Angiogenesis, Receptors
Application Notes ELISA: antibody detection limit dilution 1:64000.
Western blot: Approx 100 kDa band observed in Human lysates of cell line A549 (calculated MW of 92.0 kDa according to NP_000132.1 and of 92.1 kDa according to NP_075259.2). Recommended concentration: 0.3-1 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (Internal Region) antibody ABIN334399 (0.3µg/ml) staining of A549 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
General Easton, Pooley, Dunning et al.: "Genome-wide association study identifies novel breast cancer susceptibility loci." in: Nature, Vol. 447, Issue 7148, pp. 1087-93, 2007 (PubMed).

McGrath, Lee, Buring et al.: "Novel breast cancer risk alleles and endometrial cancer risk." in: International journal of cancer. Journal international du cancer, Vol. 123, Issue 12, pp. 2961-4, 2008 (PubMed).

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