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FGFR2 antibody (Fibroblast Growth Factor Receptor 2) (Internal Region)

Details for Product anti-FGFR2 Antibody No. ABIN334399, Supplier: Login to see
Antigen
  • FGFR2
  • FGFR2IIIb
  • bek
  • bfr-1
  • cd332
  • cek3
  • cfd1
  • ect1
  • fgfr-2
  • jws
  • k-sam
  • kgfr
  • tk14
  • tk25
  • xfgfr2
  • DKFZp469H1521
  • BBDS
  • BEK
  • BFR-1
  • CD332
  • CEK3
  • CFD1
  • ECT1
  • JWS
  • K-SAM
  • KGFR
  • TK14
  • TK25
  • AU043015
  • AW556123
  • Bek
  • Fgfr-2
  • Fgfr-7
  • Fgfr7
  • KGFRTr
  • svs
  • FGF-R
  • fgfr72IIIb
  • FGFR
  • fc56c05
  • wu:fc56c05
Alternatives
anti-Human FGFR2 antibody for Immunohistochemistry
Epitope
Internal Region
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34
23
21
14
8
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6
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5
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
260
56
47
3
2
2
2
2
2
1
1
1
1
Host
Goat
201
51
12
1
Clonality
Polyclonal
Conjugate
This FGFR2 antibody is un-conjugated
12
11
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10
9
9
1
1
1
1
1
1
1
1
1
1
1
Methode Type
Peptide ELISA
Application
ELISA, Western Blotting (WB)
192
127
88
69
54
45
18
11
10
8
2
1
1
Supplier
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Immunogen Peptide with sequence C-GREKEITASPDY, from the internal region of the protein sequence according to NP_000132.3, NP_075259.4, NP_001138385.1, NP_001138386.1, NP_001138387.1, NP_001138388.1, NP_001138390.1, NP_001138391.1.
Blocking Peptide Blocking peptide for this product available: ABIN369132
Specificity This antibody is expected to recognise all reported isoforms except isoform 7 (NP_001138389.1). The immunizing peptide represents part of the extracellular domain.
Cross-Reactivity Mouse (Murine), Rat (Rattus), Dog (Canine), Pig (Porcine), Cow (Bovine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name FGFR2 (FGFR2 Antibody Abstract)
Background Synonyms: FGFR2, fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome), BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM
Gene ID 2263, 14183, 25022
NCBI Accession NP_000132, NP_001138387, NP_001138388, NP_001138386, NP_001138385, NP_001138391, NP_001138390, NP_075259
Research Area Growth Factors, Lineage Markers, Tyrosine Kinases, Angiogenesis, Receptors
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes ELISA: antibody detection limit dilution 1:64000.
Western blot: Approx 100 kDa band observed in Human lysates of cell line A549 (calculated MW of 92.0 kDa according to NP_000132.1 and of 92.1 kDa according to NP_075259.2). Recommended concentration: 0.3-1 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
 image for anti-FGFR2 antibody (Fibroblast Growth Factor Receptor 2) (Internal Region) (ABIN334399) ABIN334399 (0.3µg/ml) staining of A549 lysate (35µg protein in RIPA buffer). Primary ...
Background publications McGrath, Lee, Buring et al.: "Novel breast cancer risk alleles and endometrial cancer risk." in: International journal of cancer. Journal international du cancer, Vol. 123, Issue 12, pp. 2961-4, 2008 (PubMed).

Easton, Pooley, Dunning et al.: "Genome-wide association study identifies novel breast cancer susceptibility loci. ..." in: Nature, Vol. 447, Issue 7148, pp. 1087-93, 2007 (PubMed).