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Details for Product No. ABIN350307

Endothelin Receptor Type B (EDNRB) (C-Term) antibody

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Antigen
Synonyms ETB, Etb, Ednra, ABCDS, ET-B, ET-BR, ETBR, ETRB, HSCR, HSCR2, WS4A, ETR-b, ETb, Sox10m1, EDNRB, abcds, etb, etrb, hscr, hscr2, ednrb
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN350307
Quantity 100 µL
Price
454.67 $   Plus shipping costs $45.00
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Availability Will be delivered in 7 to 8 Business Days

Product details

Target Details Application Details Handling References Alternatives back to top
Immunogen A synthetic peptide from the c-terminal of human Endothelin B receptor (EDNRB) conjugated to an immunogenic carrier protein was used as the immunogen. The peptide is homologous in rat and mouse.
Specificity Specific for KCNE1L.
Purification Unpurified, concentrated culture supernatant.
Purity IgG

Target Details

Application Details Handling References Alternatives back to top
Alternative Name Endothelin B receptor (EDNRB)
Background Function: Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Subcellular location: Cell membrane, Multi-pass membrane protein.
Tissue specificity: Expressed in placental stem villi vessels, but not in cultured placental villi smooth muscle cells. Also known as: Endothelin receptor non-selective type, EDNRB, ETRB.
UniProt A5HKJ1

Application Details

Target Details Handling References Alternatives back to top
Application Notes A concentration of 10-50 µg/mL is recommended.
The optimal concentration should be determined by the end user.
Not yet tested in other applications.
Restrictions For Research Use only

Handling

Target Details Application Details References Alternatives back to top
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handling Advice Avoid freeze and thaw cycles.
Storage -20 °C
Storage Comment Maintain the lyophilised/reconstituted antibodies frozen at -20 °C for long term storage and refrigerated at 2-8 °C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
Expiry Date 12 months

References

Target Details Application Details Handling Alternatives back to top
Arai, Nakao, Hosoda et al.: "[Molecular cloning of human endothelin receptors and their expression in vascular endothelial cells and smooth muscle cells]" in: Japanese circulation journal, Vol. 56 Suppl 5, pp. 1303-7, 1993 (PubMed).

Nakamuta, Takayanagi, Sakai et al.: "Cloning and sequence analysis of a cDNA encoding human non-selective type of endothelin receptor." in: Biochemical and biophysical research communications, Vol. 177, Issue 1, pp. 34-9, 1991 (PubMed).

Elshourbagy, Korman, Wu et al.: "Molecular characterization and regulation of the human endothelin receptors." in: The Journal of biological chemistry, Vol. 268, Issue 6, pp. 3873-9, 1993 (PubMed).

Tsutsumi, Liang, Jones: "Novel endothelin B receptor transcripts with the potential of generating a new receptor." in: Gene, Vol. 228, Issue 1-2, pp. 43-9, 1999 (PubMed).

Pingault, Girard, Bondurand et al.: "SOX10 mutations in chronic intestinal pseudo-obstruction suggest a complex physiopathological mechanism." in: Human genetics, Vol. 111, Issue 2, pp. 198-206, 2002 (PubMed).

Alternatives

Target Details Application Details Handling References back to top
Alternatives for antigen "Endothelin Receptor Type B (EDNRB)", type "Antibodies"
Hosts (75), (7), (3)
Reactivities (78), (48), (41), (35), (34), (34), (34), (2)
Applications (42), (35), (25), (20), (16), (10), (10), (7), (5), (2), (2), (2)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (10), (8), (5), (5), (3), (2), (2), (1), (1), (1), (1), (1)
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