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EDNRB Products

(Endothelin Receptor Type B (EDNRB))
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011].

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Featured EDNRB Categories

EDNRB Antibodies

High quality antibodies with extensive validation data.

EDNRB ELISA Kits

Reliable ELISA kits for a wide range of species.

EDNRB Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended EDNRB Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p), IF
Validations
  • (4)
Cat. No. ABIN390760
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN7180300
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (3)
Cat. No. ABIN7151760
Quantity 100 μg
Datasheet Datasheet

Recommended EDNRB ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966517
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966516
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955574
Quantity 96 tests
Datasheet Datasheet

Recommended EDNRB Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352333
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352332
Quantity 25 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7395518
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our EDNRB products

Rizvi, Camara, Kandror, Roberts, Schieren, Maniatis, Rabadan: "Single-cell topological RNA-seq analysis reveals insights into cellular differentiation and development." in: Nature biotechnology, Vol. 35, Issue 6, pp. 551-560, (2017) (PubMed).

Kobayashi, Yoshimoto, Yamamoto, Kimura, Okuda: "Roles of EDNs in regulating oviductal NO synthesis and smooth muscle motility in cows." in: Reproduction (Cambridge, England), Vol. 151, Issue 6, pp. 615-22, (2016) (PubMed).

Park, Mima, Li, Rask-Madsen, He, Mizutani, Katagiri, Maeda, Wu, Khamaisi, Preil, Maddaloni, Sørensen, Rasmussen, Huang, King: "Insulin decreases atherosclerosis by inducing endothelin receptor B expression." in: JCI insight, Vol. 1, Issue 6, (2016) (PubMed).

Prayitnaningsih, Sujuti, Effendi, Abdullah, Anandita, Yohana, Permatasari, Widodo: "Neuropathy optic glaucomatosa induced by systemic hypertension through activation endothelin-1 signaling pathway in central retinal artery in rats." in: International journal of ophthalmology, Vol. 9, Issue 11, pp. 1568-1577, (2016) (PubMed).

Cook, Brais, Qian, Hak, Corrie: "Endothelin-1 and endothelin B receptor expression in pancreatic adenocarcinoma." in: Journal of clinical pathology, Vol. 68, Issue 4, pp. 309-13, (2015) (PubMed).

Tanaka, Sho, Takayama, Wakatsuki, Matsumoto, Migita, Ito, Hamada, Nakajima: "Endothelin B receptor expression correlates with tumour angiogenesis and prognosis in oesophageal squamous cell carcinoma." in: British journal of cancer, Vol. 110, Issue 4, pp. 1027-33, (2014) (PubMed).

Comellas, Briva, Dada, Butti, Trejo, Yshii, Azzam, Litvan, Chen, Lecuona, Pesce, Yanagisawa, Sznajder: "Endothelin-1 impairs alveolar epithelial function via endothelial ETB receptor." in: American journal of respiratory and critical care medicine, Vol. 179, Issue 2, pp. 113-22, (2009) (PubMed).

Jones, Brockbank, Mobbs, Le Good, Soma-Haddrick, Heuze, Langham, Timms, Newham, Needham: "The orphan G-protein coupled receptor RDC1: evidence for a role in chondrocyte hypertrophy and articular cartilage matrix turnover." in: Osteoarthritis and cartilage, Vol. 14, Issue 6, pp. 597-608, (2006) (PubMed).

Ehrenreich, Nau, Dembowski, Hasselblatt, Barth, Hahn, Schilling, Sirén A-L, Brück: "Endothelin b receptor deficiency is associated with an increased rate of neuronal apoptosis in the dentate gyrus." in: Neuroscience, Vol. 95, Issue 4, pp. 993-1001, (2000) (PubMed).

Synonyms and alternative names related to EDNRB

endothelin receptor type B (EDNRB), endothelin receptor type B (Ednrb), endothelin receptor type B (ednrb), ABCDS, abcds, Ednra, EDNRB, ET-B, ET-BR, ETB, Etb, ETb, etb, ETBR, ETR-b, ETRB, etrb, HSCR, hscr, HSCR2, hscr2, Sox10m1, WS4A

Protein level used designations for EDNRB

  • endothelin B receptor
  • endothelin receptor non-selective type
  • ET-B
  • ET-BR
  • endothelin receptor subtype B
  • endothelin-B receptor
  • endothelin ETB receptor
  • piebald
  • endothelin receptor B
  • endothelin receptor type B
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