A synthetic peptide from AA 170-220 of the GAT domain of human GGA1 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in many other species including rat mouse xenopus zebrafish.
GGA1
Reactivity: Human
Host: Rabbit
Polyclonal
FITC
Application Notes
IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
Handling Advice
Avoid freeze and thaw cycles.
Storage
4 °C,-20 °C
Storage Comment
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
FUNCTION: Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif. SUBCELLULAR LOCATION: Golgi apparatus trans-Golgi network membrane, Peripheral membrane protein. Endosome membrane, Peripheral membrane protein. TISSUE SPECIFICITY: Ubiquitously expressed.