Pro-Hepcidin (AA 39-59) antibody
Reactivity: Mouse
IHC, WB
Host: Rabbit
Polyclonal
unconjugated
(1 reference)-
- Target
- Pro-Hepcidin
- Binding Specificity
- AA 39-59
- Reactivity
- Mouse
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Immunohistochemistry (IHC), Western Blotting (WB)
- Purpose
- Rabbit antibody to pro Hepcidin (39-59)
- Specificity
- Specific for Hepcidin.
- Cross-Reactivity
- Mouse
- Cross-Reactivity (Details)
- Other species not yet tested.
- Purification
- IgG
- Immunogen
- A synthetic peptide from AA 39-59 of pro region of mouse Hepcidin conjugated to blue carrier protein has been used as the antigen.
- Isotype
- IgG
-
- Application Notes
- IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
- Handling Advice
- Avoid freeze and thaw cycles.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- Expiry Date
- 12 months
-
-
: "The kidney hepcidin/ferroportin axis controls iron reabsorption and determines the magnitude of kidney and systemic iron overload." in: Kidney international, Vol. 100, Issue 3, pp. 559-569, (2021) (PubMed).
-
: "The kidney hepcidin/ferroportin axis controls iron reabsorption and determines the magnitude of kidney and systemic iron overload." in: Kidney international, Vol. 100, Issue 3, pp. 559-569, (2021) (PubMed).
-
- Target
- Pro-Hepcidin
- Alternative Name
- pro Hepcidin
- Background
- FUNCTION: Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages. May also have antimicrobial activity. SUBCELLULAR LOCATION: Secreted. Tissue specificity: Highly expressed in the liver and to a much lesser extent in the heart.
- UniProt
- Q9EQ21
-
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