Did you know that you can buy products from over 140 different suppliers from us?

Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (C-Term) antibody

Details for Product No. ABIN374505
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms
hadh2, im:6899159, wu:fj61f03, zgc:101605, abad, camr, erab, hcd2, hsd10, mhbd, mrpp2, mrx17, mrx31, mrxs10, schad, sdr5c1, HADH2, HSD17B10, 17b-HSD10, ABAD, CAMR, DUPXp11.22, ERAB, HCD2, MHBD, MRPP2, ... show more
hadh2, im:6899159, wu:fj61f03, zgc:101605, abad, camr, erab, hcd2, hsd10, mhbd, mrpp2, mrx17, mrx31, mrxs10, schad, sdr5c1, HADH2, HSD17B10, 17b-HSD10, ABAD, CAMR, DUPXp11.22, ERAB, HCD2, MHBD, MRPP2, MRX17, MRX31, MRXS10, SCHAD, SDR5C1, 17bHSD10, Ads9, Hadh2 show less
Epitope
C-Term
(9), (6), (6), (5), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Dog (Canine), Human, Monkey, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
(76), (35), (22), (2), (2), (2), (2), (2), (1)
Host
Goat
(52), (22), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(64), (27), (25), (16), (10), (7), (6), (3), (3), (2), (2)
Pubmed 1 reference available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN374505
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Peptide with sequence CIRLDGAIRMQP, from the C Terminus of the protein sequence
Specificity This antibody reacts to HSD17B10. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse, Rat, Canine, Bovine.
Purification Affinity chromatography
Alternative Name HSD17B10 / ERAB
Background ERAB is a member of the short-chain dehydrogenase/reductase superfamily. This mitochondrial protein catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. It has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD, a disorder characterized by neurological abnormalities, including psychomotor retardation and loss of mental and motor skills). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. Abundant in human liver, kidney and gonads, but it is present in only negligible amounts in skeletal muscle. At the sub-cellular level, in normal tissues, this protein is located in mithocondria. It is over- expressed in Neurons of patients with Alzheimer's disease.
Alternate names: 17-beta-HSD10, 17-beta-hydroxysteroid dehydrogenase 10, 3-hydroxy-2-methylbutyryl-CoA dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase type II, 3-hydroxyacyl-CoA dehydrogenase type-2, Endoplasmic reticulum-associated amyloid beta-peptide-binding protein, HADH2, MRPP2, Mitochondrial Marker, Mitochondrial ribonuclease P protein 2, SCHAD, Short-chain type dehydrogenase/reductase XH98G2, Type II HADH, XH98G2
Gene ID 3028
NCBI Accession 9606
UniProt Q99714
Research Area Hormones, Receptors
Application Notes Peptide ELISA: 1/32000. Western Blot: 0.3 - 2 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0,5 mg/mL
Buffer Tris buffered saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Supplier Images
anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (C-Term) antibody anti-Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (C-Term) antibody
Background publications He, Schulz, Yang: "A human brain L-3-hydroxyacyl-coenzyme A dehydrogenase is identical to an amyloid beta-peptide-binding protein involved in Alzheimer's disease." in: The Journal of biological chemistry, Vol. 273, Issue 17, pp. 10741-6, 1998 (PubMed).

Validation Images
back to top