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HSD17B10 Products

(Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

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This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008].

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Featured HSD17B10 Categories

HSD17B10 Antibodies

High quality antibodies with extensive validation data.

HSD17B10 ELISA Kits

Reliable ELISA kits for a wide range of species.

HSD17B10 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HSD17B10 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application ICC, IF, IHC (p), WB
Validations
  • (8)
Cat. No. ABIN2854703
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application FACS, IF, IHC, IHC (p), WB
Validations
  • (7)
Cat. No. ABIN1498724
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC (p), WB
Validations
  • (7)
Cat. No. ABIN3042460
Quantity 100 μg
Datasheet Datasheet

Recommended HSD17B10 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6956639
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6975066
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1381117
Quantity 96 tests
Datasheet Datasheet

Recommended HSD17B10 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3081210
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3131307
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5711745
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our HSD17B10 products

Kristofiková, Bocková, Hegnerová, Bartos, Klaschka, Rícný, Rípová, Homola: "Enhanced levels of mitochondrial enzyme 17beta-hydroxysteroid dehydrogenase type 10 in patients with Alzheimer disease and multiple sclerosis." in: Molecular bioSystems, Vol. 5, Issue 10, pp. 1174-9, (2009) (PubMed).

Tilton, Haidacher, Lejeune, Zhang, Zhao, Kurosky, Brasier, Denner: "Diabetes-induced changes in the renal cortical proteome assessed with two-dimensional gel electrophoresis and mass spectrometry." in: Proteomics, Vol. 7, Issue 10, pp. 1729-42, (2007) (PubMed).

Takuma, Yao, Huang, Xu, Chen, Luddy, Trillat, Stern, Arancio, Yan: "ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 19, Issue 6, pp. 597-8, (2005) (PubMed).

Lustbader, Cirilli, Lin, Xu, Takuma, Wang, Caspersen, Chen, Pollak, Chaney, Trinchese, Liu, Gunn-Moore, Lue, Walker, Kuppusamy, Zewier, Arancio, Stern, Yan, Wu: "ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease." in: Science (New York, N.Y.), Vol. 304, Issue 5669, pp. 448-52, (2004) (PubMed).

Kissinger, Rejto, Pelletier, Thomson, Showalter, Abreo, Agree, Margosiak, Meng, Aust, Vanderpool, Li, Tempczyk-Russell, Villafranca: "Crystal structure of human ABAD/HSD10 with a bound inhibitor: implications for design of Alzheimer's disease therapeutics." in: Journal of molecular biology, Vol. 342, Issue 3, pp. 943-52, (2004) (PubMed).

He, Merz, Yang, Pullakart, Mehta, Schulz, Yang: "Function of human brain short chain L-3-hydroxyacyl coenzyme A dehydrogenase in androgen metabolism." in: Biochimica et biophysica acta, Vol. 1484, Issue 2-3, pp. 267-77, (2000) (PubMed).

He, Schulz, Yang: "A human brain L-3-hydroxyacyl-coenzyme A dehydrogenase is identical to an amyloid beta-peptide-binding protein involved in Alzheimer's disease." in: The Journal of biological chemistry, Vol. 273, Issue 17, pp. 10741-6, (1998) (PubMed).

Synonyms and alternative names related to HSD17B10

hydroxysteroid (17-beta) dehydrogenase 10 (HSD17B10), hydroxysteroid (17-beta) dehydrogenase 10 (hsd17b10), hydroxysteroid 17-beta dehydrogenase 10 (HSD17B10), hydroxysteroid (17-beta) dehydrogenase 10 L homeolog (hsd17b10.L), hydroxysteroid (17-beta) dehydrogenase 10 (Hsd17b10), 17b-HSD10, 17bHSD10, abad, ABAD, Ads9, camr, CAMR, DUPXp11.22, erab, ERAB, hadh2, HADH2, Hadh2, hcd2, HCD2, hsd10, HSD17B10, im:6899159, mhbd, MHBD, mrpp2, MRPP2, mrx17, MRX17, mrx31, MRX31, mrxs10, MRXS10, schad, SCHAD, sdr5c1, SDR5C1, wu:fj61f03, zgc:101605

Protein level used designations for HSD17B10

  • hydroxysteroid (17-beta) dehydrogenase 10
  • 3-hydroxyacyl-CoA dehydrogenase type-2
  • hydroxyacyl-Coenzyme A dehydrogenase, type II
  • 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
  • AB-binding alcohol dehydrogenase
  • amyloid-beta peptide binding alcohol dehydrogenase
  • endoplasmic reticulum-associated amyloid beta-peptide-binding protein
  • mitochondrial RNase P subunit 2
  • mitochondrial ribonuclease P protein 2
  • short chain L-3-hydroxyacyl-CoA dehydrogenase type 2
  • short chain dehydrogenase/reductase family 5C, member 1
  • short chain type dehydrogenase/reductase XH98G2
  • 17-beta-HSD 10
  • 17-beta-hydroxysteroid dehydrogenase 10
  • 3-hydroxyacyl-CoA dehydrogenase type II
  • hydroxyacyl-Coenzyme A dehydrogenase type II
  • mitochondrial RNase P protein 2
  • type II HADH
  • amyloid beta-peptide binding protein
  • short chain L-3-hydroxyacyl-CoA dehydrogenase
  • hydroxyacyl-Coenzyme A dehydrogenase, type II hydroxyacyl-Coenzyme A
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