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HSD17B10 antibody (C-Term)

HSD17B10 Reactivity: Human WB, IF, IHC (p), ICC, IHC (wm) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2854703
  • Target See all HSD17B10 Antibodies
    HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
    Binding Specificity
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 52
    • 23
    • 17
    • 3
    • 2
    • 2
    • 2
    Human
    Host
    • 46
    • 6
    • 1
    Rabbit
    Clonality
    • 49
    • 4
    Polyclonal
    Conjugate
    • 32
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This HSD17B10 antibody is un-conjugated
    Application
    • 29
    • 15
    • 15
    • 13
    • 11
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Whole Mount) (IHC (wm))
    Cross-Reactivity
    Human, Mouse, Rat, Zebrafish (Danio rerio)
    Characteristics
    Rabbit Polyclonal antibody to ERAB (hydroxysteroid (17-beta) dehydrogenase 10)
    ERAB antibody
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ERAB. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: Neuro 2A , GL261 , PC-12 , HeLaS3 , Molt-4

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
    Alternative Name
    hydroxysteroid 17-beta dehydrogenase 10 (HSD17B10 Products)
    Synonyms
    hadh2 antibody, im:6899159 antibody, wu:fj61f03 antibody, zgc:101605 antibody, abad antibody, camr antibody, erab antibody, hcd2 antibody, hsd10 antibody, mhbd antibody, mrpp2 antibody, mrx17 antibody, mrx31 antibody, mrxs10 antibody, schad antibody, sdr5c1 antibody, HADH2 antibody, HSD17B10 antibody, 17b-HSD10 antibody, ABAD antibody, CAMR antibody, DUPXp11.22 antibody, ERAB antibody, HCD2 antibody, MHBD antibody, MRPP2 antibody, MRX17 antibody, MRX31 antibody, MRXS10 antibody, SCHAD antibody, SDR5C1 antibody, 17bHSD10 antibody, Ads9 antibody, Hadh2 antibody, hydroxysteroid (17-beta) dehydrogenase 10 antibody, hydroxysteroid 17-beta dehydrogenase 10 antibody, hydroxysteroid (17-beta) dehydrogenase 10 L homeolog antibody, HSD17B10 antibody, hsd17b10 antibody, hsd17b10.L antibody, Hsd17b10 antibody
    Background
    This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

    Cellular Localization: Mitochondrion
    Molecular Weight
    27 kDa
    Gene ID
    3028
    UniProt
    Q99714
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