HSD17B10 antibody (AA 140-172)

Catalog No. ABIN6243230

Product Details anti-HSD17B10 Antibody

Target: HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

Binding Specificity: AA 140-172

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD17B10 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Predicted Reactivity: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HSD17B10 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 140-172 amino acids from the Central region of human HSD17B10.

Clone: RB56913

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:25. WB: 1:2000. IHC-P: 1:25. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for HSD17B10

Target: HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

Alternative Name: HSD17B10 (HSD17B10 Products)

Synonyms: hadh2 antibody, im:6899159 antibody, wu:fj61f03 antibody, zgc:101605 antibody, abad antibody, camr antibody, erab antibody, hcd2 antibody, hsd10 antibody, mhbd antibody, mrpp2 antibody, mrx17 antibody, mrx31 antibody, mrxs10 antibody, schad antibody, sdr5c1 antibody, HADH2 antibody, HSD17B10 antibody, 17b-HSD10 antibody, ABAD antibody, CAMR antibody, DUPXp11.22 antibody, ERAB antibody, HCD2 antibody, MHBD antibody, MRPP2 antibody, MRX17 antibody, MRX31 antibody, MRXS10 antibody, SCHAD antibody, SDR5C1 antibody, 17bHSD10 antibody, Ads9 antibody, Hadh2 antibody, hydroxysteroid (17-beta) dehydrogenase 10 antibody, hydroxysteroid 17-beta dehydrogenase 10 antibody, hydroxysteroid (17-beta) dehydrogenase 10 L homeolog antibody, HSD17B10 antibody, hsd17b10 antibody, hsd17b10.L antibody, Hsd17b10 antibody

Background: Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).

Molecular Weight: 26923

UniProt: Q99714