CNR1 antibody (Internal Region)

Catalog No. ABIN374611

This Goat Polyclonal antibody specifically detects CNR1 in WB. It exhibits reactivity toward Human, Rat, Mouse, Dog and Cat.

Quick Overview for CNR1 antibody (Internal Region) (ABIN374611)

Target: CNR1 (Cannabinoid Receptor 1 (CNR1))

Reactivity: Human, Rat, Mouse, Dog, Cat

Host: Goat

Clonality: Polyclonal

Conjugate: This CNR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CNR1 Antibody

Binding Specificity: Internal Region

Specificity: This antibody reacts to Cannabinoid receptor 1.

Cross-Reactivity (Details): Species reactivity (expected):Rat, Canine.
Species reactivity (tested):Human, Mouse.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-HTSEDGKVQVTRPDQ, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/32000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CNR1

Target: CNR1 (Cannabinoid Receptor 1 (CNR1))

Alternative Name: Cannabinoid Receptor 1

Background: Cannabinoid Receptor 1 is one of two main cannabinoid receptors which are G-protein-coupled receptors inhibiting adenylate cyclase activity. The CB(1) receptor is densely distributed in areas of the brain related to motor control, cognition, emotional responses, motivated behaviour and homeostasis. Cannabinoid receptors have a complex molecular architecture that allows a single receptor to recognize multiple classes of compounds and produce an array of distinct downstream effects. Recent pharmacological advances have led to the synthesis of cannabinoid receptor agonists and antagonists. This has helped in the development of new strategies for the treatment of pain, obesity, neurological diseases including multiple sclerosis, emotional disturbances such as anxiety and other psychiatric disorders including drug and alcohol addiction.Synonyms: CANN6, CB-R, CB1, CNR, CNR1

Gene ID: 1268, 9606

UniProt: P21554

Pathways: Feeding Behaviour