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Details for Product No. ABIN375216

MutY Homolog (E. Coli) (MUTYH) (C-Term) antibody

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Antigen
Synonyms CYP2C, MYH, Myh, Mutyha, Mutyhb, Mutyhc, Mutyhbeta, Mutyhalpha, 5730495A01Rik, MUTYH, MGC145569
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN375216
Quantity 0.1 mg
Price
346.50 $   Plus shipping costs $45.00
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anti-MutY Homolog (E. Coli) (MUTYH) (C-Term) antibody

Product details

Target Details Application Details Handling Images References Alternatives back to top
Immunogen Peptide with sequence C-HISTDAHSLNSAAQ, from the C Terminus of the protein sequence
Specificity This antibody reacts to MUTYH.
Purification Affinity chromatography

Target Details

Application Details Handling Images References Alternatives back to top
Alternative Name MUTYH
Background MYH is the eukaryotic homolog to the E. coli protein MutY. It was first identified in HeLa cells and nicks DNA replication errors, specifically A/G mismatches. MYH is involved in oxidative DNA damage repair. It initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. It possesses both adenine and 2-OH-A DNA glycosylase activities.
Alternate names: A/G-specific adenine DNA glycosylase, MYH, MutY homolog
Gene ID 4595
NCBI Accession NP_001041636.1
UniProt Q9UIF7

Application Details

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Application Notes Peptide ELISA: 1/16000. Western Blot: 0.1 - 0.3µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

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Format Liquid
Concentration 0,5 mg/mL
Buffer Tris buffered saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months

References

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Background publications Slupska, Baikalov, Luther et al.: "Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage." in: Journal of bacteriology, Vol. 178, Issue 13, pp. 3885-92, 1996 (PubMed).

Alternatives

Target Details Application Details Handling Images References back to top
Alternatives for antigen "MutY Homolog (E. Coli) (MUTYH)", type "Antibodies"
Hosts (41), (5), (4)
Reactivities (49), (26), (23), (12), (12), (12)
Applications (36), (24), (10), (9), (8), (4), (2), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (4), (4), (2), (1), (1), (1), (1), (1), (1)
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