MutY Homolog (E. Coli) (MUTYH) (C-Term) antibody

Details for Product No. ABIN375216
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Antigen
Synonyms MUTYH, MGC145569, CYP2C, MYH, 5730495A01Rik, Mutyha, Mutyhalpha, Mutyhb, Mutyhbeta, Mutyhc, Myh
Epitope
C-Term
(6), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(63), (36), (32)
Host
Goat
(52), (6), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(49), (26), (16), (10), (8), (7), (4), (3), (2), (2), (2), (1), (1)
Pubmed 1 reference available
Quantity 0.1 mg
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Catalog No. ABIN375216
368.50 $
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Immunogen Peptide with sequence C-HISTDAHSLNSAAQ, from the C Terminus of the protein sequence
Specificity This antibody reacts to MUTYH.
Purification Affinity chromatography
Alternative Name MUTYH
Background MYH is the eukaryotic homolog to the E. coli protein MutY. It was first identified in HeLa cells and nicks DNA replication errors, specifically A/G mismatches. MYH is involved in oxidative DNA damage repair. It initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. It possesses both adenine and 2-OH-A DNA glycosylase activities.Synonyms: A/G-specific adenine DNA glycosylase, MYH, MutY homolog
Gene ID 4595
NCBI Accession NP_001041636
UniProt Q9UIF7
Application Notes Peptide ELISA: 1/16000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0,5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
anti-MutY Homolog (E. Coli) (MUTYH) (C-Term) antibody anti-MutY Homolog (E. Coli) (MUTYH) (C-Term) antibody
Background publications Slupska, Baikalov, Luther et al.: "Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage." in: Journal of bacteriology, Vol. 178, Issue 13, pp. 3885-92, 1996 (PubMed).

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