Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) (N-Term), (AA 35-63) antibody

Details for Product No. ABIN389291
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Antigen
Synonyms CD-MPR, MPR 46, MPR-46, MPR46, SMPR, CDMPR, Mpr46, m6pr, MGC68896, MGC130765, zgc:77757, wu:fj81h11, MGC89423, M6PR, mprd
Epitope
N-Term, AA 35-63
(9), (4), (1), (1)
Reactivity
Human, Mouse (Murine)
(25), (9), (7), (4), (3)
Host
Rabbit
(19), (4), (2), (1), (1), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(22), (13), (5), (2), (1), (1), (1), (1)
Pubmed 1 reference available
Catalog no. ABIN389291
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This M6PR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-63 AA from the N-terminal region of human M6PR.
Clone RB15076
Isotype Ig
Specificity This M6PR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42~71 amino acids from the N-term region of human M6PR.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name M6PR
Background M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.
Synonyms: Cation-dependent mannose-6-phosphate receptor, CD Man-6-P receptor, CD-MPR, 46 kDa mannose 6-phosphate receptor, MPR 46, M6PR, MPR46, MPRD
Molecular Weight 30993 DA
Gene ID 4074
UniProt P20645
Research Area Stem Cells, Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) (N-Term), (AA 35-63) antibody Western blot analysis of M6PR Antibody (N-term)(ABIN389291) in mouse brain tissue lysates (35 µg/lane). M6PR (arrow) was detected using the purified polyclonal antibody.
anti-Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) (N-Term), (AA 35-63) antibody (2) Formalin-fixed and paraffin-embedded human testis tissue reacted with M6PR antibody (N-term) (ABIN389291), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Background publications Pérez-Victoria, Mardones, Bonifacino: "Requirement of the human GARP complex for mannose 6-phosphate-receptor-dependent sorting of cathepsin D to lysosomes." in: Molecular biology of the cell, Vol. 19, Issue 6, pp. 2350-62, 2008 (PubMed).

Hosts (19), (4), (2), (1), (1), (1)
Reactivities (25), (9), (7), (4), (3)
Applications (22), (13), (5), (2), (1), (1), (1), (1)
Conjugates (2), (2), (2)
Epitopes (9), (4), (1), (1)
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