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M6PR Products

(Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))
This gene encodes the gamma sunbunit of the N-acetylglucosamine-1-phosphotransferase complex. This hexameric complex, composed of alpha, beta and gamma subunits, catalyzes the first step in synthesis of a mannose 6-phosphate lysosomal recognition marker. This enzyme complex is necessary for targeting of lysosomal hydrolases to the lysosome. Mutations in the gene encoding the gamma subunit have been associated with mucolipidosis IIIC, also known as mucolipidosis III gamma.[provided by RefSeq, Feb 2010].

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Featured M6PR Categories

M6PR Antibodies

High quality antibodies with extensive validation data.

M6PR ELISA Kits

Reliable ELISA kits for a wide range of species.

M6PR Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended M6PR Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7147043
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, FACS
Validations
  • (3)
Cat. No. ABIN650726
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (3)
Cat. No. ABIN7262102
Quantity 200 μL
Datasheet Datasheet

Recommended M6PR ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6957643
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1744445
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1125650
Quantity 96 tests
Datasheet Datasheet

Recommended M6PR Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1309980
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3083853
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133413
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our M6PR products

Ohka, Tan, Ishiyama, Ogasawara, Hanasaka, Ishida, Hagiwara, Liu, Chong, Hanaki, Schiavo: "The uncoating of EV71 in mature late endosomes requires CD-M6PR." in: Biology open, Vol. 11, Issue 9, (2022) (PubMed).

Ginwala, Caruso, Khan, Pattekar, Chew, Corley, Loonawat, Jacobson, Sreedhar, Ndhlovu, Jain: "HTLV-1 Infection and Neuropathogenesis in the Context of Rag1(-/-)γc(-/-) (RAG1-Hu) and BLT Mice." in: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, Vol. 12, Issue 3, pp. 504-520, (2017) (PubMed).

Armstrong, Mattsson, Appelqvist, Janefjord, Sandin, Agholme, Olsson, Svensson, Blennow, Zetterberg, Kågedal: "Lysosomal network proteins as potential novel CSF biomarkers for Alzheimer's disease." in: Neuromolecular medicine, Vol. 16, Issue 1, pp. 150-60, (2014) (PubMed).

Frei, Jeon, Kilcher, Moest, Henning, Jost, Plückthun, Mercer, Aebersold, Carreira, Wollscheid: "Direct identification of ligand-receptor interactions on living cells and tissues." in: Nature biotechnology, Vol. 30, Issue 10, pp. 997-1001, (2012) (PubMed).

Steffan, Williams, Welbourne, Cardelli: "HGF-induced invasion by prostate tumor cells requires anterograde lysosome trafficking and activity of Na+-H+ exchangers." in: Journal of cell science, Vol. 123, Issue Pt 7, pp. 1151-9, (2010) (PubMed).

Kinzel, Boldt, Davis, Burtscher, Trümbach, Diplas, Attié-Bitach, Wurst, Katsanis, Ueffing, Lickert: "Pitchfork regulates primary cilia disassembly and left-right asymmetry." in: Developmental cell, Vol. 19, Issue 1, pp. 66-77, (2010) (PubMed).

Zygmunt, McKinnon, Herr, Lala, Han: "HCG increases trophoblast migration in vitro via the insulin-like growth factor-II/mannose-6 phosphate receptor." in: Molecular human reproduction, Vol. 11, Issue 4, pp. 261-7, (2005) (PubMed).

Synonyms and alternative names related to M6PR

insulin like growth factor 2 receptor (IGF2R), mannose-6-phosphate receptor, cation dependent (M6PR), mannose-6-phosphate receptor, cation dependent (M6pr), mannose-6-phosphate receptor (cation dependent) L homeolog (m6pr.L), mannose-6-phosphate receptor (cation dependent) (m6pr), mannose-6-phosphate receptor (cation dependent) S homeolog (m6pr.S), mannose-6-phosphate receptor (cation dependent) (Ethha_1678), Cation-dependent mannose-6-phosphate receptor (mprd), N-acetylglucosamine-1-phosphate transferase gamma subunit (GNPTG), C16orf27, CD-MPR, CD222, CDMPR, CIMPR, GNPTAG, LP2537, M6P-R, m6pr, M6PR, MGC68896, MGC89423, MGC130765, MPR-46, MPR1, MPR 46, MPR46, Mpr46, mprd, MPRI, RJD9, SMPR, wu:fj81h11, zgc:77757

Protein level used designations for M6PR

  • 300 kDa mannose 6-phosphate receptor
  • CI Man-6-P receptor
  • CI-MPR
  • IGF-II receptor
  • M6P/IGF2 receptor
  • M6P/IGF2R
  • M6PR
  • MPR 300
  • cation-independent mannose-6 phosphate receptor
  • cation-independent mannose-6-phosphate receptor
  • insulin-like growth factor II receptor
  • 46-kDa mannose 6-phosphate receptor
  • CD Man-6-P receptor
  • Mr 46,000 Man6PR
  • cation-dependent mannose-6-phosphate receptor
  • small mannose 6-phosphate receptor
  • 46 kDa mannose 6-phosphate receptor
  • MPR 46
  • CD-MPR
  • mannose-6-phosphate receptor (cation dependent)
  • Mannose 6-Phosphate Receptor
  • Cation-dependent mannose-6-phosphate receptor
  • N-acetylglucosamine-1-phosphotransferase subunit gamma
  • UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma
  • glcNAc-1-phosphotransferase subunit gamma
  • N-acetylglucosamine-1-phosphotransferase, gamma subunit
  • insulin-like growth factor 2 receptor
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