BUD31 antibody (N-Term)

Catalog No. ABIN390083

The Rabbit Polyclonal anti-BUD31 antibody has been validated for WB. It is suitable to detect BUD31 in samples from Human. There is 1 publication available.

Quick Overview for BUD31 antibody (N-Term) (ABIN390083)

Target: BUD31 (BUD31 Homolog (BUD31))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BUD31 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB01825

Product Details anti-BUD31 Antibody

Binding Specificity: AA 21-50, N-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This EDG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human EDG2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-BUD31 antibody (ABIN390083)

Boucharaba, Serre, Guglielmi, Bordet, Clézardin, Peyruchaud: "The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 25, pp. 9643-8, (2006) (PubMed).

Target Details for BUD31

Target: BUD31 (BUD31 Homolog (BUD31))

Alternative Name: EDG2

Background: The EDG2 integral membrane protein is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion.

Molecular Weight: 41109

Gene ID: 1902

NCBI Accession: NP_001392, NP_476500

UniProt: Q92633