Endothelin Receptor Type B (EDNRB) (AA 409-439), (C-Term) antibody

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Antigen
Synonyms EDNRB, abcds, etb, etrb, hscr, hscr2, ednrb, ABCDS, ET-B, ET-BR, ETB, ETBR, ETRB, HSCR, HSCR2, WS4A, Ednra, Etb, ETR-b, ETb, Sox10m1
Epitope
AA 409-439, C-Term
(20), (16), (6), (3), (3), (3), (3), (3), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(90), (49), (44)
Host
Rabbit
(83), (13), (3), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(52), (30), (30), (22), (14), (10), (9), (7), (6), (3), (2), (1)
Pubmed 1 reference available
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Quantity 400 μL
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Immunogen This EDN_ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-439 AA from the C-terminal region of human EDN_.
Clone RB19285
Isotype Ig
Specificity This EDNRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 413~442 amino acids from the C-terminal region of human EDNRB.
Predicted Reactivity Cow (Bovine),Pig (Porcine),Rat (Rattus),Rabbit
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name EDNRB (EDNRB Antibody Abstract)
Background EDNRB is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene.
Synonyms: Endothelin B receptor, ET-B, Endothelin receptor non-selective type, ETRB, EDNRB
Molecular Weight 49644 DA
Gene ID 1910
UniProt P24530
Research Area Cell Signaling, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Endothelin Receptor Type B (EDNRB) (AA 409-439), (C-Term) antibody (ABIN390760) Western blot analysis of EDNRB Antibody (C-term) (ABIN390760) in mouse cerebellum tis...
Immunohistochemistry (IHC) image for anti-Endothelin Receptor Type B (EDNRB) (AA 409-439), (C-Term) antibody (ABIN390760) EDNRB Antibody (C-term) (ABIN390760) IHC analysis in formalin fixed and paraffin embe...
Flow Cytometry (FACS) image for anti-Endothelin Receptor Type B (EDNRB) (AA 409-439), (C-Term) antibody (ABIN390760) FKBP10 Antibody (N-term) (ABIN391572) flow cytometric analysis of NCI-H460 cells (bot...
Background publications MacClellan, Howard, Cole et al.: "Relation of candidate genes that encode for endothelial function to migraine and stroke: the Stroke Prevention in Young Women study." in: Stroke; a journal of cerebral circulation, Vol. 40, Issue 10, pp. e550-7, 2009 (PubMed).

Catalog No. ABIN390760
$324.50
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