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Details for Product No. ABIN390760

Endothelin Receptor Type B (EDNRB) (C-Term), (AA 409-439) antibody

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Antigen
Synonyms ETB, Etb, Ednra, ABCDS, ET-B, ET-BR, ETBR, ETRB, HSCR, HSCR2, WS4A, ETR-b, ETb, Sox10m1, EDNRB, abcds, etb, etrb, hscr, hscr2, ednrb
Epitope
»Alternatives C-Term, AA 409-439
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
Pubmed 1 reference available
Catalog no. ABIN390760
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This EDN_ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-439 AA from the C-terminal region of human EDN_.
Clone RB19285
Isotype Ig
Specificity This EDNRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 413~442 amino acids from the C-terminal region of human EDNRB.
Predicted Reactivity Cow (Bovine),Pig (Porcine),Rat (Rattus),Rabbit
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name EDNRB
Background EDNRB is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene.
Synonyms: Endothelin B receptor, ET-B, Endothelin receptor non-selective type, ETRB, EDNRB
Molecular Weight 49644 DA
Gene ID 1910
UniProt P24530
Research Area Cell Signaling, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50,IF : 1:10-50,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications MacClellan, Howard, Cole et al.: "Relation of candidate genes that encode for endothelial function to migraine and stroke: the Stroke Prevention in Young Women study." in: Stroke; a journal of cerebral circulation, Vol. 40, Issue 10, pp. e550-7, 2009 (PubMed).

Alternatives for antigen "Endothelin Receptor Type B (EDNRB)", type "Antibodies"
Hosts (75), (7), (3)
Reactivities (78), (48), (40), (35), (34), (34), (34), (2)
Applications (42), (34), (25), (20), (16), (10), (10), (6), (5), (2), (2), (2)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (11), (8), (5), (3), (3), (2), (1), (1), (1), (1), (1), (1)
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