anti-EPH Receptor A7 antibody (EPHA7) (AA 896-925)

Details for Product anti-EPHA7 Antibody No. ABIN391899
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Synonyms fc51g03, wu:fc51g03, si:dkey-23k6.1, EHK3, HEK11, Cek11, Ebk, Ehk3, Hek11, Mdk1, CEPHA7
AA 896-925, C-Term
(28), (22), (15), (14), (14), (12), (9), (6), (6), (5), (5), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
(128), (46), (38), (1)
(115), (18), (2), (1)
Clonality (Clone)
Polyclonal ()
This EPH Receptor A7 antibody is un-conjugated
(7), (7), (7), (6), (6), (6), (1), (1), (1), (1), (1), (1), (1), (1)
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(99), (88), (42), (14), (12), (10), (9), (3), (2), (1)
Pubmed 5 references available
Quantity 400 μL
Shipping to United States ( )
Availability Will be delivered in 2 to 4 Business Days
Immunogen This EphA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 896-925 AA from the C-terminal region of human EphA7.
Clone RB1641-RB1642
Isotype Ig
Specificity This EphA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 904~933 amino acids from the C-terminal region of human EphA7.
Predicted Reactivity Chicken
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name EphA7 (EPHA7 Antibody Abstract)
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).
Synonyms: Ephrin type-A receptor 7, Tyrosine-protein kinase receptor EHK-3, Eph-homology kinase-3, Receptor protein-tyrosine kinase HEK11
Molecular Weight 112096 DA
Gene ID 2045
UniProt Q15375
Research Area Phospho-specific antibodies, Stem Cells, Cell Signaling, Protein Modifications, Cell Cycle, Transcription Factors, Signaling, Metabolism, Cell Structure
Pathways RTK Signaling
Application Notes WB = 1:1000, IHC (p) = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 1.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-EPH Receptor A7 antibody (EPHA7) (AA 896-925) (ABIN391899) Western blot analysis of anti-EphA7 Pab (ABIN391899) in NCI-H460 cell lysate. EphA7 (...
Western Blotting (WB) image for anti-EPH Receptor A7 antibody (EPHA7) (AA 896-925) (ABIN391899) Western blot analysis of EPHA7 (arrow) using EphA7 Antibody (C-term) (ABIN391899). 29...
Immunohistochemistry (IHC) image for anti-EPH Receptor A7 antibody (EPHA7) (AA 896-925) (ABIN391899) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Product cited in: Kim, Ibrahim, Wang et al.: "EphA7 regulates spiral ganglion innervation of cochlear hair cells." in: Developmental neurobiology, 2015 (PubMed).

Brantley-Sieders, Jiang, Sarma et al.: "Eph/ephrin profiling in human breast cancer reveals significant associations between expression level and clinical outcome." in: PLoS ONE, Vol. 6, Issue 9, pp. e24426, 2011 (PubMed).

Wang, Li, Ma et al.: "Differential expression of EphA7 receptor tyrosine kinase in gastric carcinoma." in: Human pathology, Vol. 38, Issue 11, pp. 1649-56, 2007 (PubMed).

Background publications Holder, Klein: "Eph receptors and ephrins: effectors of morphogenesis." in: Development (Cambridge, England), Vol. 126, Issue 10, pp. 2033-44, 1999 (PubMed).

Fox, Holst, Chute et al.: "cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases." in: Oncogene, Vol. 10, Issue 5, pp. 897-905, 1995 (PubMed).

Catalog No. ABIN391899
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