Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) (C-Term) antibody

Details for Product No. ABIN486848
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms zgc:103550, CKN1, CSA, UVSS2, Ckn1, 2410022P04Rik, 2810431L23Rik, 4631412O06Rik, B130065P18Rik, Csa
Epitope
C-Term
(10), (5), (4), (4), (3), (3), (2), (1), (1), (1), (1)
Reactivity
Human
(52), (21), (14), (3), (3), (1), (1)
Host
Rabbit
(44), (8)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(40), (10), (10), (9), (8), (8), (6), (4), (2), (2), (1)
Pubmed 1 reference available
Quantity 50 µg
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN486848
289.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide directed towards the C terminal of human ERCC8
Sequence QELYSGSRDC NILAWVPSLY EPVPDDDETT TKSQLNPAFE DAWSSSDEEG
Predicted Reactivity Human : 100 %, Dog : 90 %, Horse : 80 %, Rabbit : 70 %
Characteristics This is a rabbit polyclonal antibody against ERCC8. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name ERCC8
Background ERCC8 (excision repair cross-complementing rodent repair deficiency, complementation group 8 isoform 1) is a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcript
Molecular Weight 44 kDa
Gene ID 1161
NCBI Accession NP_000073, NM_000082
UniProt Q13216
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 396 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) (C-Term) antibody WB Suggested Anti-ERCC8 Antibody Titration: 0.1-5.0ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) (C-Term) antibody (2) anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) (C-Term) antibody (Image 2)
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) (C-Term) antibody (3) anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) (C-Term) antibody (Image 3)
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) (C-Term) antibody (4) Host: Rabbit
Target Name: ERCC8
Sample Tissue: MCF7 Whole Cell lysates
Antibody Dilution: 1.0 µg/mL
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) (C-Term) antibody (5) Host: Rabbit
Target Name: ERCC8
Sample Tissue: Human Adult Placenta
Antibody Dilution: 1.0 µg/mL
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) (C-Term) antibody (6) Host: Rabbit
Target Name: ERCC8
Sample Tissue: Human Fetal Heart
Antibody Dilution: 1.0 µg/mL
anti-Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8) (C-Term) antibody (7) Host: Rabbit
Target Name: ERCC8
Sample Tissue: Human Fetal Lung
Antibody Dilution: 1.0 µg/mL
Background publications Groisman, Polanowska, Kuraoka et al.: "The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage." in: Cell, Vol. 113, Issue 3, pp. 357-67, 2003 (PubMed).

Validation Images
Did you look for something else?
back to top