TRPV5 antibody (N-Term)

Catalog No. ABIN487228

This Rabbit Polyclonal antibody specifically detects TRPV5 in WB and IHC. It exhibits reactivity toward Human, Rat, Mouse, Cow, Dog, Pig, Guinea Pig, Horse and Rabbitand has been mentioned in 1 publication.

Quick Overview for TRPV5 antibody (N-Term) (ABIN487228)

Target: TRPV5 (Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5))

Reactivity: Human, Rat, Mouse, Cow, Dog, Pig, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPV5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TRPV5 Antibody

Binding Specificity: N-Term

Sequence: MLQQKRILES PLLRASKEND LSVLRQLLLD CTCDVRQRGA LGETALHIAA

Predicted Reactivity: Cow: 85%, Dog: 85%, Guinea Pig: 85%, Horse: 77%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 77%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against TRPV5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRPV5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 729 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TRPV5 antibody (ABIN487228)

Cha, Wu, Huang: "Protein kinase C inhibits caveolae-mediated endocytosis of TRPV5." in: American journal of physiology. Renal physiology, Vol. 294, Issue 5, pp. F1212-21, (2008) (PubMed).

Target Details for TRPV5

Target: TRPV5 (Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5))

Alternative Name: TRPV5

Background: TRPV5 is a member of the transient receptor family and the TrpV subfamily. TRPV5, a calcium-selective channel, has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. TRPV5 forms homotetramers or heterotetramers and is activated by a low internal calcium level.This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2486 AF304464.1 86-2571
Alias Symbols: CAT2, ECAC1, OTRPC3
Protein Interaction Partner: EWSR1, CALB1, S100A10, ANXA2,
Protein Size: 729

Molecular Weight: 82 kDa

Gene ID: 56302

NCBI Accession: NM_019841, NP_062815

UniProt: Q9NQA5