ANTXR2 antibody (Internal Region)

Catalog No. ABIN498028

Product Details anti-ANTXR2 Antibody

Target: ANTXR2 (Anthrax Toxin Receptor 2 (ANTXR2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat, Dog, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This ANTXR2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-HEGLKLANEQ IQK

Specificity: This antibody is expected to recognize both reported isoforms (NP_477520.2, NP_001139266.1).

Cross-Reactivity (Details): Species reactivity (expected):Canine (Dog), Bovine.
Species reactivity (tested):Human, Mouse, Rat.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal regoin of the protein sequence according to NP_477520.2, NP_001139266.1. Genename: ANTXR2

Application Details

Application Notes: Peptide ELISA: Limit Dilution: 1/16000. Western blot: 0.3-1 μg/mL. Approx 60 kDa band observed in Human, Mouse and Rat Kidneylysates (calculated MW of approx 50 kDa according to NP_477520.2, NP_001139266.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ANTXR2

Target: ANTXR2 (Anthrax Toxin Receptor 2 (ANTXR2))

Alternative Name: Anthrax Toxin Receptor 2 (ANTXR2 Products)

Background: This gene encodes a receptor for anthrax toxin. The protein binds to collagen IV and laminin, suggesting that it may be involved in extracellular matrix adhesion. Mutations in this gene cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. [provided by RefSeq].Synonyms: ANTXR2, CMG-2, CMG2, Capillary morphogenesis gene 2 protein

Gene ID: 118429

NCBI Accession: NP_477520

UniProt: P58335