ARL15 antibody (Center)

Catalog No. ABIN499335

This anti-ARL15 antibody is a Rabbit Polyclonal antibody detecting ARL15 in WB, IHC (p) and EIA. Suitable for Human, Mouse and Rat.

Quick Overview for ARL15 antibody (Center) (ABIN499335)

Target: ARL15 (ADP-Ribosylation Factor-Like 15 (ARL15))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARL15 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-ARL15 Antibody

Binding Specificity: Center

Specificity: This antibody reacts to ARL15.

Purification: Affinity chromatography purified via peptide column

Immunogen: ARL15 antibody was raised against a 17 amino acid peptide near the center of human ARL15.

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: ARL15 antibody can be used for detection of Arl15 at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for ARL15

Target: ARL15 (ADP-Ribosylation Factor-Like 15 (ARL15))

Alternative Name: ARL15 / ARFRP2

Background: ADP-ribosylation factors (ARFs) are highly conserved guanine nucleotide binding proteins that enhance the ADP-ribosyltransferase activity of cholera toxin. ARFs are important in eukaryotic vesicular trafficking pathways and they play an essential role in the activation of phospholipase D (PC-PLD). ARL15 (ADP-ribosylation factor-like 15), is a member of the ARF family of the Ras superfamily of small GTPases that are known to be involved in multiple regulatory pathways altered in human carcinogenesis. Other members of this protein family include ARL11, thought to be a tumor suppressor and may play a role in the regulation of apoptosis, ARL2 which plays an important role in microtubule dynamics and cell cycle progression, and ARL4, which may play a role in neurogenesis during embryonic development. The gene encoding ARL15 maps to chromosome 5p15 in humans. At least three isoforms of ARL15 are known to exist.Synonyms: ADP-ribosylation factor-like protein 15, ADP-ribosylation factor-related protein 2, ARF-related protein 2

Gene ID: 54622

NCBI Accession: NP_061960

UniProt: Q9NXU5