SLC22A12 antibody (N-Term)
Quick Overview for SLC22A12 antibody (N-Term) (ABIN502474)
Target
See all SLC22A12 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- SMLENFSAAV PSHRCWAPLL DNSTAQASIL GSLSPEALLA ISIPPGPNQR
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Predicted Reactivity
- Human: 100%
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Characteristics
- This is a rabbit polyclonal antibody against SLC22A12. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SLC22A12
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 553 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SLC22A12 (Solute Carrier Family 22 (Organic Anion/urate Transporter), Member 12 (SLC22A12))
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Alternative Name
- SLC22A12
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Background
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SLC22A12 is required for efficient urate re-absorption in the kidney. SLC22A12 regulates blood urate levels. SLC22A12 mediates saturable urate uptake by facilitating the exchange of urate against organic anions.The protein encoded by this gene is a urate transporter and urate-anion exchanger which regulates the level of urate in the blood. This protein is an integral membrane protein primarily found in kidney. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: OAT4L, RST, URAT1
Protein Interaction Partner: PDZK1,
Protein Size: 553 -
Molecular Weight
- 59 kDa
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Gene ID
- 116085
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NCBI Accession
- NM_144585, NP_653186
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UniProt
- Q96S37
Target
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