ICOS antibody (FITC)

Catalog No. ABIN610259

Product Details anti-ICOS Antibody (FITC)

Target: ICOS (Inducible T-Cell Co-Stimulator (ICOS))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ICOS antibody is conjugated to FITC

Application: Flow Cytometry (FACS), ELISA, Functional Studies (Func)

Specificity: Recombinant and cell surface CD278 (ICOS).

Purification: Protein A purified

Immunogen: Human HPB-MLT cells, recombinant human CD278(ICOS)-muIg.

Clone: ANC6C6-A3

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: ELISA, Flo, Func

Usage: Flow Cytometry: 1:50 (or use 1.6?l of concentrated stock per 5 x 10^5 cell test), Function: Blocks binding of Recombinant CD275-muIg to CD278. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5 % Glycerol, 0.2 % BSA, 0.04 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Product is photosensitive and should be protected from light.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Protect from light.

Target Details for ICOS

Target: ICOS (Inducible T-Cell Co-Stimulator (ICOS))

Alternative Name: ICOS / CD278 (ICOS Products)

Background: Name/Gene ID: ICOS

Synonyms: ICOS, AILIM, CD278, CVID1, Inducible costimulator, Inducible T-cell co-stimulator, CD278 antigen, Inducible T-cell costimulator

Gene ID: 29851

UniProt: Q9Y6W8

Pathways: Cancer Immune Checkpoints