CD163 antibody (PE)
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- Target See all CD163 Antibodies
- CD163
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD163 antibody is conjugated to PE
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Application
- Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC), Fluorescence Microscopy (FM)
- Specificity
- The CD163 antigen is the cysteine-rich human scavenger receptor protein (p155, M130) found on mononuclear phagocytes, monocytes, and macrophages. CD163 is up-regulated on mononuclear phagocytes by IL-4, IL-6 and dexamethasone and serves as a receptor for the hemoglobin / haptoglobin complex. Expression of CD163 is restricted to cells of monocyte lineage and increases as the monocytes mature into macrophages. CD163 is present on all CD14 + monocytes, most CD64+ monocytes, and demonstrates higher expression on CD16+ monocytes. Stimulation of monocytes and macrophages by lipopolysacharide (LPS), IL-10, and tumor necrosis factor alpha (TNF-α) causes shedding of CD163 from the cell surface into plasma or supernata
- Clone
- MAC2-158
- Isotype
- IgG1
- Top Product
- Discover our top product CD163 Primary Antibody
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Storage
- 4 °C
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- Target
- CD163
- Alternative Name
- CD163 (CD163 Products)
- Background
- Antigen distribution: The CD163 antigen is the cysteine-rich human scavenger receptor protein (p155, M130) found on mononuclear phagocytes, monocytes, and macrophages. CD163 is up-regulated on mononuclear phagocytes by IL-4, IL-6 and dexamethasone and serves as a receptor for the hemoglobin / haptoglobin complex. Expression of CD163 is restricted to cells of monocyte lineage and increases as the monocytes mature into macrophages. CD163 is present on all CD14 + monocytes, most CD64+ monocytes, and demonstrates higher expression on CD16+ monocytes. Stimulation of monocytes and macrophages by lipopolysacharide (LPS), IL-10, and tumor necrosis factor alpha (TNF-α) causes shedding of CD163 from the cell surface into plasma or supernata. Cellular Expression: Mononuclear phagocytes, monocytes and macrophages.
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