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Junction Plakoglobin (JUP) (AA 636-663), (C-Term) antibody

Details for Product No. ABIN652942, Supplier: Login to see
Antigen
  • arvd12
  • ctnng
  • dp3
  • dpiii
  • pdgb
  • pkgb
  • plak
  • ARVD12
  • CTNNG
  • DP3
  • DPIII
  • PDGB
  • PKGB
  • D930025P04Rik
  • PG
  • jup
  • cb80
  • danPG
  • fb11b06
  • wu:fb11b06
Epitope
AA 636-663, C-Term
56
13
7
5
4
3
3
3
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
185
82
76
18
8
4
4
2
1
Host
Rabbit
122
57
17
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
5
5
5
3
3
3
3
2
2
2
2
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
152
61
60
43
42
36
23
18
13
8
4
3
1
1
Supplier
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Immunogen This JUP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 636-663 AA from the C-terminal region of human JUP.
Clone RB23555
Isotype Ig
Specificity This JUP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 642~672 amino acids from the C-terminal region of human JUP.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Pig (Porcine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name JUP (JUP Antibody Abstract)
Background JUP is a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.
Synonyms: Catenin gamma, Desmoplakin III, Desmoplakin-3, Junction plakoglobin, JUP, CTNNG, DP3
Molecular Weight 81745 DA
Gene ID 3728
UniProt P14923
Research Area Signaling, Protein Modifications
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Junction Plakoglobin (JUP) (AA 636-663), (C-Term) antibody (ABIN652942) Western blot analysis of JUP Antibody (C-term) (ABIN652942) in MCF-7 cell line lysate...
Immunohistochemistry (IHC) image for anti-Junction Plakoglobin (JUP) (AA 636-663), (C-Term) antibody (ABIN652942) Formalin-fixed and paraffin-embedded human lung carcinoma reacted with JUP Antibody (...
Flow Cytometry (FACS) image for anti-Junction Plakoglobin (JUP) (AA 636-663), (C-Term) antibody (ABIN652942) JUP Antibody (C-term)(ABIN652942) flow cytometry analysis of MCF-7 cells (bottom hist...
Background publications Arnemann, Spurr, Wheeler et al.: "Chromosomal assignment of the human genes coding for the major proteins of the desmosome junction, desmoglein DGI (DSG), desmocollins DGII/III (DSC), desmoplakins DPI/II (DSP), and plakoglobin DPIII (JUP)." in: Genomics, Vol. 10, Issue 3, pp. 640-5, 1991 (PubMed).