JUP Products
(Junction Plakoglobin (JUP))
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This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene\; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008].
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Featured JUP Categories
JUP Antibodies
High quality antibodies with extensive validation data.
JUP ELISA Kits
Reliable ELISA kits for a wide range of species.
JUP Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended JUP Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, ICC
Validations
- (1)
- (6)
Cat. No.
ABIN969225
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF, IHC, ELISA, ICC
Validations
- (11)
Cat. No.
ABIN6260497
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC
Validations
- (7)
Cat. No.
ABIN7101634
Quantity
20 μL
Datasheet
Datasheet
Recommended JUP ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6957240
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968085
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380988
Quantity
96 tests
Datasheet
Datasheet
Recommended JUP Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1308342
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3094617
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3134786
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our JUP products
: "Haemorrhagic snake venom metalloproteases and human ADAMs cleave LRP5/6, which disrupts cell-cell adhesions in vitro and induces haemorrhage in vivo." in: The FEBS journal, Vol. 284, Issue 11, pp. 1657-1671, (2017) (PubMed).: "Vitronectin and dermcidin serum levels predict the metastatic progression of AJCC I-II early-stage melanoma." in: International journal of cancer, Vol. 139, Issue 7, pp. 1598-607, (2016) (PubMed).
: "Plakoglobin interacts with the transcription factor p53 and regulates the expression of 14-3-3σ." in: Journal of cell science, Vol. 126, Issue Pt 14, pp. 3031-42, (2013) (PubMed).
: "Antibody phage display assisted identification of junction plakoglobin as a potential biomarker for atherosclerosis. ..." in: PLoS ONE, Vol. 7, Issue 10, pp. e47985, (2012) (PubMed).
: "Epstein-Barr virus latent membrane protein-1 effects on junctional plakoglobin and induction of a cadherin switch." in: Cancer research, Vol. 69, Issue 14, pp. 5734-42, (2009) (PubMed).
: "Axon behavior in the olfactory nerve reflects the involvement of catenin-cadherin mediated adhesion." in: The Journal of comparative neurology, Vol. 499, Issue 6, pp. 979-89, (2007) (PubMed).
: "Tyrosine phosphorylation of plakoglobin causes contrary effects on its association with desmosomes and adherens junction components and modulates beta-catenin-mediated transcription." in: Molecular and cellular biology, Vol. 23, Issue 20, pp. 7391-402, (2003) (PubMed).
: "Biogenesis of N-cadherin-dependent cell-cell contacts in living fibroblasts is a microtubule-dependent kinesin-driven mechanism." in: Molecular biology of the cell, Vol. 13, Issue 1, pp. 285-301, (2002) (PubMed).
: "Suprabasal desmoglein 3 expression in the epidermis of transgenic mice results in hyperproliferation and abnormal differentiation." in: Molecular and cellular biology, Vol. 22, Issue 16, pp. 5846-58, (2002) (PubMed).
: "Restoration of E-cadherin-based cell-cell adhesion by overexpression of nectin in HSC-39 cells, a human signet ring cell gastric cancer cell line." in: Oncogene, Vol. 21, Issue 26, pp. 4108-19, (2002) (PubMed).
Synonyms and alternative names related to JUP
junction plakoglobin (JUP), junction plakoglobin (Jup), junction plakoglobin (jup), junction plakoglobin L homeolog (jup.L), junction plakoglobin (Tsp_06656), Junction plakoglobin (plak), junction plakoglobin a (jupa), junction plakoglobin S homeolog (jup.S), ARVD12, arvd12, cb80, CTNNG, ctnng, D930025P04Rik, danPG, DP3, dp3, DPIII, dpiii, fb11b06, jup, PDGB, pdgb, PG, PKGB, pkgb, plak, wu:fb11b06Protein level used designations for JUP
- catenin (cadherin-associated protein), gamma 80kDa
- desmoplakin III
- desmoplakin-3
- gamma-catenin (plakoglobin)
- desmoplakin 3
- junction plakoglobin
- Junction plakoglobin
- junction plakoglobin-like
- gamma-catenin
- plakoglobin
- gama-catenin
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