SF3B1 antibody (N-Term)
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- Target See all SF3B1 Antibodies
- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
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Binding Specificity
- AA 374-402, N-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SF3B1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Predicted Reactivity
- X
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This SF3B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-402 amino acids from the N-terminal region of human SF3B1.
- Clone
- RB33758
- Isotype
- Ig Fraction
- Top Product
- Discover our top product SF3B1 Primary Antibody
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- Application Notes
- WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50. IHC-P: 1:25
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- SF3B1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- Expiry Date
- 6 months
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- Target
- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
- Alternative Name
- SF3B1 (SF3B1 Products)
- Background
- This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].
- Molecular Weight
- 145830
- Gene ID
- 23451
- NCBI Accession
- NP_036565
- UniProt
- O75533
- Pathways
- Chromatin Binding
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