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SF3B1 antibody (N-Term)

SF3B1 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB33758 unconjugated
Catalog No. ABIN657676
  • Target See all SF3B1 Antibodies
    SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
    Binding Specificity
    • 15
    • 9
    • 7
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 374-402, N-Term
    Reactivity
    • 57
    • 40
    • 33
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 68
    • 4
    Rabbit
    Clonality
    • 57
    • 15
    Polyclonal
    Conjugate
    • 31
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SF3B1 antibody is un-conjugated
    Application
    • 52
    • 24
    • 23
    • 13
    • 13
    • 11
    • 8
    • 6
    • 4
    • 4
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    X
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This SF3B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-402 amino acids from the N-terminal region of human SF3B1.
    Clone
    RB33758
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SF3B1 Primary Antibody
  • Application Notes
    WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50. IHC-P: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    SF3B1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Expiry Date
    6 months
  • Target
    SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
    Alternative Name
    SF3B1 (SF3B1 Products)
    Background
    This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].
    Molecular Weight
    145830
    Gene ID
    23451
    NCBI Accession
    NP_036565
    UniProt
    O75533
    Pathways
    Chromatin Binding
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