SF3B1 antibody (AA 186-378)

Catalog No. ABIN7170618

Product Details anti-SF3B1 Antibody

Target: SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))

Binding Specificity: AA 186-378

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Splicing factor 3B subunit 1 protein (186-378AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SF3B1

Target: SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))

Alternative Name: SF3B1 (SF3B1 Products)

Synonyms: Cus1 antibody, SAP145 antibody, SF3B145 antibody, SF3b1 antibody, SF3b150 antibody, Hsh155 antibody, MDS antibody, PRP10 antibody, PRPF10 antibody, SAP155 antibody, SF3b155 antibody, 155kDa antibody, 2810001M05Rik antibody, AA409119 antibody, Prp10 antibody, TA-8 antibody, Targ4 antibody, hsh155 antibody, prp10 antibody, prpf10 antibody, sap155 antibody, SF3B1 antibody, Sap155 antibody, wu:fb99f09 antibody, splicing factor 3b subunit 2 antibody, splicing factor 3b subunit 1 antibody, splicing factor 3b, subunit 1 antibody, splicing factor 3b subunit 1 S homeolog antibody, SF3B2 antibody, SF3B1 antibody, Sf3b1 antibody, sf3b1.S antibody, sf3b1 antibody

Background:

Background: Subunit of the splicing factor SF3B required for \\\'A\\\' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the \\\'E\\\' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.

Aliases: Hsh155 antibody, OTTHUMP00000205700 antibody, OTTHUMP00000205702 antibody, OTTHUMP00000225001 antibody, OTTHUMP00000225002 antibody, Pre mRNA processing 10 antibody, Pre mRNA splicing factor SF3b, 155 kDa subunit antibody, Pre-mRNA splicing factor SF3b 155 kDa subunit antibody, Pre-mRNA-splicing factor SF3b 155 kDa subunit antibody, PRP10 antibody, PRPF10 antibody, SAP 155 antibody, SAP155 antibody, sf3b1 antibody, SF3B1_HUMAN antibody, SF3b155 antibody, Spliceosome associated protein 155 antibody, Spliceosome-associated protein 155 antibody, Splicing factor 3B subunit 1 antibody, Splicing factor 3b, subunit 1, 155 kDa antibody

UniProt: O75533

Pathways: Chromatin Binding