Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

DYRK2 antibody (C-Term)

DYRK2 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB34467 unconjugated
Catalog No. ABIN657991
  • Target See all DYRK2 Antibodies
    DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
    Binding Specificity
    • 15
    • 10
    • 8
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 521-549, C-Term
    Reactivity
    • 42
    • 31
    • 22
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 55
    • 7
    • 1
    Rabbit
    Clonality
    • 56
    • 7
    Polyclonal
    Conjugate
    • 26
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DYRK2 antibody is un-conjugated
    Application
    • 56
    • 33
    • 27
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Mouse Dyrk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-549 amino acids from the C-terminal region of mouse Dyrk2.
    Clone
    RB34467
    Isotype
    Ig Fraction
    Top Product
    Discover our top product DYRK2 Primary Antibody
  • Application Notes
    WB: 1:2000. WB: 1:1000. WB: 1:8000. IHC-P: 1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Mouse Dyrk2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Expiry Date
    6 months
  • Target
    DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
    Alternative Name
    Dyrk2 (DYRK2 Products)
    Synonyms
    DYRK2 antibody, fc18c09 antibody, si:ch211-266a5.8 antibody, wu:fa09g03 antibody, wu:fc18c09 antibody, 1810038L18Rik antibody, dual specificity tyrosine phosphorylation regulated kinase 2 antibody, dual specificity tyrosine-phosphorylation-regulated kinase 2 antibody, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 antibody, DYRK2 antibody, CpipJ_CPIJ014802 antibody, dyrk2 antibody, Dyrk2 antibody
    Background
    Role in the regulation of cellular growth and/or development. Regulates TP53 by phosphorylation on Ser-46 to induce apoptosis in response to DNA damage, functioning downstream of ATM. Inactivates GYS1 by phosphorylation at Ser-641, and potentially also a second phosphorylation site, thus regulating glycogen synthesis. Phosphorylates EIF2B5 at Ser-544, enabling its subsequent phosphorylation and inhibition by GSK3, and may play a more general role in the priming of GSK3 substrates (By similarity).
    Molecular Weight
    66556
    Gene ID
    69181
    NCBI Accession
    NP_001014412
    UniProt
    Q5U4C9
    Pathways
    Regulation of Carbohydrate Metabolic Process
You are here:
Support