DYRK2 antibody (C-Term)

Catalog No. ABIN2789798

The Rabbit Polyclonal anti-DYRK2 antibody (ABIN2789798) specifically detects DYRK2 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for DYRK2 antibody (C-Term) (ABIN2789798)

Target: DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYRK2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DYRK2 Antibody

Binding Specificity: C-Term

Purpose: DYRK2 Antibody - C-terminal region

Sequence: LFLDFLKQCL EWDPAVRMTP GQALRHPWLR RRLPKPPTGE KTSVKRITES

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against DYRK2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64302-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DYRK2

Target: DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))

Alternative Name: DYRK2

Background:

Background Information: DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro.

Gene Name: Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2

Alternative Symbols: FLJ21217, FLJ21365

Protein Name: Dual specificity tyrosine-phosphorylation-regulated kinase 2

Molecular Weight: 60kDa

Gene ID: 8445

NCBI Accession: NP_003574

UniProt: Q92630

Pathways: Regulation of Carbohydrate Metabolic Process